AtlasInfectionsAcute hepatitis

Acute hepatitis B

4Curable or preventable in mostAI-generated
Burden-over-time charts — how many people this disease affects and whether that number is rising or falling — are coming to this page. The treatability read, milestones, and live trial pipeline below are current.

Milestones

dot size = significance
199020002010202020251995 — Lamivudine approved (FDA)1996 — Hepatitis b virus hbsag surface protein antigen approved (FDA)2000 — Hepatitis b virus s protein, pre-s1 protein and pre-s2 protein virus like particles approved (FDA)2001 — Tenofovir disoproxil approved (FDA)2002 — Adefovir dipivoxil approved (FDA)2002 — Peginterferon alfa-2a approved (FDA)2005 — Entecavir anhydrous approved (FDA)2006 — Telbivudine approved (FDA)2009 — Hepatitis b immune globulin approved (FDA)2015 — Tenofovir alafenamide approved (FDA)
1995: Drug approval — Lamivudine approved (FDA). 1996: Drug approval — Hepatitis b virus hbsag surface protein antigen approved (FDA). 2000: Drug approval — Hepatitis b virus s protein, pre-s1 protein and pre-s2 protein virus like particles approved (FDA). 2001: Drug approval — Tenofovir disoproxil approved (FDA). 2002: Drug approval — Adefovir dipivoxil approved (FDA). 2002: Drug approval — Peginterferon alfa-2a approved (FDA). 2005: Drug approval — Entecavir anhydrous approved (FDA). 2006: Drug approval — Telbivudine approved (FDA). 2009: Drug approval — Hepatitis b immune globulin approved (FDA). 2015: Drug approval — Tenofovir alafenamide approved (FDA)

What's being tested now

2001: 1 trials started2008: 1 trials started2011: 1 trials started2013: 1 trials started2014: 2 trials started2015: 1 trials started2016: 3 trials started2018: 4 trials started2019: 5 trials started2020: 9 trials started2021: 11 trials started2022: 13 trials started2023: 17 trials started2024: 49 trials started2025: 55 trials started2026: 45 trials started20102020202655

Trials started per year, stacked by phase (darker = later phase). Source: ClinicalTrials.gov via Clin2, which tracks studies recruiting in recent years — early years undercount.

See all 206 active Chronic Hepatitis B trials on Clin2 →

Related

Burden estimates: IHME Global Burden of Disease Study. Drug indications: ChEMBL (CC BY-SA). Trial data: ClinicalTrials.gov via Clin2. Velocity, acceleration, and turning points are computed by Clin2 — how this page is made. Treatability describes what medicine can do, not what is available everywhere. This page describes populations, not people, and is not medical advice.