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Acute lymphoid leukemia

4Curable or preventable in mostAI-generated
Burden-over-time charts — how many people this disease affects and whether that number is rising or falling — are coming to this page. The treatability read, milestones, and live trial pipeline below are current.

Milestones

dot size = significance
199020002010202020251994 — Asparaginase approved (FDA)1994 — Pegaspargase approved (FDA)1997 — Rituximab approved (FDA)2001 — Imatinib approved (FDA)2004 — Clofarabine approved (FDA)2005 — Nelarabine approved (FDA)2006 — Dasatinib anhydrous approved (FDA)2011 — Asparaginase erwinia chrysanthemi approved (FDA)2012 — Ponatinib approved (FDA)2014 — Blinatumomab approved (FDA)2017 — Inotuzumab ozogamicin approved (FDA)2018 — Calaspargase pegol approved (FDA)2018 — Tisagenlecleucel approved (FDA)2023 — Crisantaspase approved (FDA)2024 — Obecabtagene autoleucel approved (FDA)
1994: Drug approval — Asparaginase approved (FDA). 1994: Drug approval — Pegaspargase approved (FDA). 1997: Drug approval — Rituximab approved (FDA). 2001: Drug approval — Imatinib approved (FDA). 2004: Drug approval — Clofarabine approved (FDA). 2005: Drug approval — Nelarabine approved (FDA). 2006: Drug approval — Dasatinib anhydrous approved (FDA). 2011: Drug approval — Asparaginase erwinia chrysanthemi approved (FDA). 2012: Drug approval — Ponatinib approved (FDA). 2014: Drug approval — Blinatumomab approved (FDA). 2017: Drug approval — Inotuzumab ozogamicin approved (FDA). 2018: Drug approval — Calaspargase pegol approved (FDA). 2018: Drug approval — Tisagenlecleucel approved (FDA). 2023: Drug approval — Crisantaspase approved (FDA). 2024: Drug approval — Obecabtagene autoleucel approved (FDA)

What's being tested now

2001: 1 trials started2004: 1 trials started2005: 1 trials started2007: 1 trials started2008: 2 trials started2009: 6 trials started2010: 2 trials started2011: 2 trials started2012: 3 trials started2013: 3 trials started2014: 7 trials started2015: 8 trials started2016: 6 trials started2017: 14 trials started2018: 13 trials started2019: 22 trials started2020: 21 trials started2021: 22 trials started2022: 44 trials started2023: 54 trials started2024: 101 trials started2025: 98 trials started2026: 94 trials started201020202026101

Trials started per year, stacked by phase (darker = later phase). Source: ClinicalTrials.gov via Clin2, which tracks studies recruiting in recent years — early years undercount.

See all 503 active Acute Lymphoblastic Leukemia trials on Clin2 →

Related

Chronic lymphoid leukemiaAcute myeloid leukemiaChronic myeloid leukemiaOther leukemia

Burden estimates: IHME Global Burden of Disease Study. Drug indications: ChEMBL (CC BY-SA). Trial data: ClinicalTrials.gov via Clin2. Velocity, acceleration, and turning points are computed by Clin2 — how this page is made. Treatability describes what medicine can do, not what is available everywhere. This page describes populations, not people, and is not medical advice.