Clin2Atlas
AtlasInfectionsRespiratory infections and tuberculosis

Upper respiratory infections

1SymptomaticAI-generated
Burden-over-time charts — how many people this disease affects and whether that number is rising or falling — are coming to this page. The treatability read, milestones, and live trial pipeline below are current.

Milestones

dot size = significance
199020002010202020251989 — Cefixime approved (FDA)1990 — Ofloxacin approved (FDA)1990 — Fluticasone propionate approved (FDA)1991 — Azithromycin approved (FDA)1991 — Cefprozil anhydrous, (e)- approved (FDA)1991 — Clarithromycin approved (FDA)1991 — Foscarnet approved (FDA)1992 — Itraconazole approved (FDA)1992 — Atovaquone approved (FDA)1993 — Tazobactam approved (FDA)1993 — Rimantadine approved (FDA)1994 — Budesonide approved (FDA)1994 — Salmeterol approved (FDA)1995 — Ceftibuten approved (FDA)1996 — Levofloxacin anhydrous approved (FDA)1996 — Cefepime approved (FDA)1996 — Hepatitis b virus hbsag surface protein antigen approved (FDA)1997 — Cefdinir approved (FDA)1997 — Bordetella pertussis filamentous hemagglutinin approved (FDA)1997 — Bordetella pertussis pertactin autotransporter approved (FDA)1999 — Moxifloxacin approved (FDA)1999 — Oseltamivir approved (FDA)1999 — Zanamivir approved (FDA)1999 — Bordetella pertussis toxin approved (FDA)2000 — Linezolid approved (FDA)2001 — Telithromycin approved (FDA)2001 — Cefditoren pivoxil approved (FDA)2001 — Anakinra approved (FDA)2001 — Ertapenem approved (FDA)2001 — Formoterol approved (FDA)2002 — Guaifenesin approved (FDA)2003 — Omalizumab approved (FDA)2004 — Tiotropium approved (FDA)2005 — Tocilizumab approved (FDA)2006 — Arformoterol approved (FDA)2007 — Influenza a virus, inactivated hemagglutinin approved (FDA)2007 — Influenza b virus, inactivated neuraminidase approved (FDA)2007 — Doripenem approved (FDA)2007 — Influenza a virus, inactivated neuraminidase approved (FDA)2007 — Influenza a virus, inactivated whole virion approved (FDA)2007 — Influenza b virus, inactivated hemagglutinin approved (FDA)2008 — Menthol approved (FDA)2008 — Influenza a virus, split virion approved (FDA)2009 — Indacaterol approved (FDA)2009 — Influenza b virus, split virion approved (FDA)2009 — Telavancin approved (FDA)2010 — Ceftaroline fosamil approved (FDA)2010 — Roflumilast approved (FDA)2011 — Influenza b virus, live attenuated approved (FDA)2011 — Influenza a virus, live attenuated approved (FDA)2012 — Aclidinium approved (FDA)2013 — Umeclidinium approved (FDA)2013 — Vilanterol approved (FDA)2014 — Peramivir anhydrous approved (FDA)2014 — Olodaterol approved (FDA)2016 — Ephedrine approved (FDA)2017 — Dupilumab approved (FDA)2017 — Hydrogen peroxide approved (FDA)2018 — Omadacycline approved (FDA)2018 — Baloxavir marboxil approved (FDA)2019 — Cefiderocol approved (FDA)2019 — Pretomanid approved (FDA)2019 — Lefamulin approved (FDA)2020 — Tozinameran approved (FDA)2020 — Influenza a virus hemagglutinin approved (FDA)2020 — Remdesivir approved (FDA)2020 — Influenza b virus hemagglutinin approved (FDA)2021 — Sotrovimab approved (FDA)2021 — Elasomeran approved (FDA)2021 — Adenovirus type 26 encoding sars-cov-2 spike glycoprotein approved (FDA)2021 — Chimpanzee adenovirus encoding sars-cov-2 spike glycoprotein approved (FDA)2021 — Sars-cov-2 virus spike protein approved (FDA)2021 — Regdanvimab approved (FDA)2022 — Sars-cov-2 virus, inactivated approved (FDA)2023 — Selvacovatein approved (FDA)2020
1989: Drug approval — Cefixime approved (FDA). 1990: Drug approval — Ofloxacin approved (FDA). 1990: Drug approval — Fluticasone propionate approved (FDA). 1991: Drug approval — Azithromycin approved (FDA). 1991: Drug approval — Cefprozil anhydrous, (e)- approved (FDA). 1991: Drug approval — Clarithromycin approved (FDA). 1991: Drug approval — Foscarnet approved (FDA). 1992: Drug approval — Itraconazole approved (FDA). 1992: Drug approval — Atovaquone approved (FDA). 1993: Drug approval — Tazobactam approved (FDA). 1993: Drug approval — Rimantadine approved (FDA). 1994: Drug approval — Budesonide approved (FDA). 1994: Drug approval — Salmeterol approved (FDA). 1995: Drug approval — Ceftibuten approved (FDA). 1996: Drug approval — Levofloxacin anhydrous approved (FDA). 1996: Drug approval — Cefepime approved (FDA). 1996: Drug approval — Hepatitis b virus hbsag surface protein antigen approved (FDA). 1997: Drug approval — Cefdinir approved (FDA). 1997: Drug approval — Bordetella pertussis filamentous hemagglutinin approved (FDA). 1997: Drug approval — Bordetella pertussis pertactin autotransporter approved (FDA). 1999: Drug approval — Moxifloxacin approved (FDA). 1999: Drug approval — Oseltamivir approved (FDA). 1999: Drug approval — Zanamivir approved (FDA). 1999: Drug approval — Bordetella pertussis toxin approved (FDA). 2000: Drug approval — Linezolid approved (FDA). 2001: Drug approval — Telithromycin approved (FDA). 2001: Drug approval — Cefditoren pivoxil approved (FDA). 2001: Drug approval — Anakinra approved (FDA). 2001: Drug approval — Ertapenem approved (FDA). 2001: Drug approval — Formoterol approved (FDA). 2002: Drug approval — Guaifenesin approved (FDA). 2003: Drug approval — Omalizumab approved (FDA). 2004: Drug approval — Tiotropium approved (FDA). 2005: Drug approval — Tocilizumab approved (FDA). 2006: Drug approval — Arformoterol approved (FDA). 2007: Drug approval — Influenza a virus, inactivated hemagglutinin approved (FDA). 2007: Drug approval — Influenza b virus, inactivated neuraminidase approved (FDA). 2007: Drug approval — Doripenem approved (FDA). 2007: Drug approval — Influenza a virus, inactivated neuraminidase approved (FDA). 2007: Drug approval — Influenza a virus, inactivated whole virion approved (FDA). 2007: Drug approval — Influenza b virus, inactivated hemagglutinin approved (FDA). 2008: Drug approval — Menthol approved (FDA). 2008: Drug approval — Influenza a virus, split virion approved (FDA). 2009: Drug approval — Indacaterol approved (FDA). 2009: Drug approval — Influenza b virus, split virion approved (FDA). 2009: Drug approval — Telavancin approved (FDA). 2010: Drug approval — Ceftaroline fosamil approved (FDA). 2010: Drug approval — Roflumilast approved (FDA). 2011: Drug approval — Influenza b virus, live attenuated approved (FDA). 2011: Drug approval — Influenza a virus, live attenuated approved (FDA). 2012: Drug approval — Aclidinium approved (FDA). 2013: Drug approval — Umeclidinium approved (FDA). 2013: Drug approval — Vilanterol approved (FDA). 2014: Drug approval — Peramivir anhydrous approved (FDA). 2014: Drug approval — Olodaterol approved (FDA). 2016: Drug approval — Ephedrine approved (FDA). 2017: Drug approval — Dupilumab approved (FDA). 2017: Drug approval — Hydrogen peroxide approved (FDA). 2018: Drug approval — Omadacycline approved (FDA). 2018: Drug approval — Baloxavir marboxil approved (FDA). 2019: Drug approval — Cefiderocol approved (FDA). 2019: Drug approval — Pretomanid approved (FDA). 2019: Drug approval — Lefamulin approved (FDA). 2020: Drug approval — Tozinameran approved (FDA). 2020: Drug approval — Influenza a virus hemagglutinin approved (FDA). 2020: Drug approval — Remdesivir approved (FDA). 2020: Drug approval — Influenza b virus hemagglutinin approved (FDA). 2021: Drug approval — Sotrovimab approved (FDA). 2021: Drug approval — Elasomeran approved (FDA). 2021: Drug approval — Adenovirus type 26 encoding sars-cov-2 spike glycoprotein approved (FDA). 2021: Drug approval — Chimpanzee adenovirus encoding sars-cov-2 spike glycoprotein approved (FDA). 2021: Drug approval — Sars-cov-2 virus spike protein approved (FDA). 2021: Drug approval — Regdanvimab approved (FDA). 2022: Drug approval — Sars-cov-2 virus, inactivated approved (FDA). 2023: Drug approval — Selvacovatein approved (FDA)

What's being tested now

2000: 2 trials started2001: 1 trials started2002: 1 trials started2004: 1 trials started2005: 1 trials started2008: 1 trials started2009: 1 trials started2010: 2 trials started2011: 2 trials started2013: 4 trials started2014: 4 trials started2015: 4 trials started2016: 5 trials started2017: 10 trials started2018: 11 trials started2019: 11 trials started2020: 102 trials started2021: 74 trials started2022: 97 trials started2023: 179 trials started2024: 245 trials started2025: 315 trials started2026: 304 trials started2000201020202026315

Trials started per year, stacked by phase (darker = later phase). Source: ClinicalTrials.gov via Clin2, which tracks studies recruiting in recent years — early years undercount.

See all 1175 active Allergic Bronchopulmonary Aspergillosis trials on Clin2 →

Related

Lower respiratory infectionsOtitis mediaCOVID-19

Burden estimates: IHME Global Burden of Disease Study. Drug indications: ChEMBL (CC BY-SA). Trial data: ClinicalTrials.gov via Clin2. Velocity, acceleration, and turning points are computed by Clin2 — how this page is made. Treatability describes what medicine can do, not what is available everywhere. This page describes populations, not people, and is not medical advice.