Clinical trials
Articular Cartilage Defect clinical trials
Below are recruiting articular cartilage defect clinical trials, each written for real people, not researchers. We’re tracking 11 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04744402RecruitingPhase 2
Cartilage repair treatment test for knee joint damage
This Phase 2 study tests CartiLife® to help repair a specific type of damaged knee cartilage. You may be considered if you have a moderate-sized cartilage defect in the knee and enough pain and function limits to need treatment.
Irvine, CaliforniaAges 18 years+ - NCT07094100Recruiting
Repairing knee cartilage with lab-grown tissue
This study tests whether lab-made cartilage can safely and effectively repair knee joint damage in adults. It may be an option if you have a cartilage defect from an injury or other cause and haven't had recent knee surgery.
Xinxiang, HenanAges 18–65 - NCT06915363Recruiting
BioPoly implant for knee cartilage repair
This trial tests a BioPoly implant to repair a small damaged cartilage spot in your knee. If you have a specific type of cartilage injury that didn't get better with other treatments, this implant may help relieve pain and improve function.
Fort Wayne, IndianaAges 30–65 - NCT06915233RecruitingPhase 3
MACI for ankle cartilage defects in adults
This trial tests a treatment called MACI for people with damaged cartilage in their ankle. It uses your own cells to grow new cartilage, which may help reduce pain and improve how you can use your ankle.
Sacramento, CaliforniaAges 17–65 - NCT05402072RecruitingPhase 1
Compare a collagen implant vs microfracture for hip cartilage damage
This Phase 1 study tests whether an “AMIC” collagen-based treatment works better or safely than the standard microfracture procedure for a specific kind of hip cartilage injury. If you have ongoing hip pain from a cartilage defect (not arthritis), you may be able to join and receive one of these surgical treatments along with a study rehab plan.
Hamilton, OntarioAges 18–55 - NCT04296487Recruiting
ACI treatment for cartilage repair after failed knee care
This trial tests a cartilage-repair procedure called ACI for people whose knee cartilage injury has not improved after at least 6 months of prior treatment. If you qualify, it may help your cartilage heal and reduce symptoms.
Lausanne, Canton of VaudAges 15–50 - NCT03588975RecruitingPhase 3
Cartilage repair for knee damage in teens
This trial tests two ways to repair damaged knee cartilage in young people: one uses your own cartilage cells grown in a lab (MACI), and the other is a standard procedure called microfracture. The goal is to see which works better to reduce pain and improve knee function, and to help you get back to normal activities.
Palo Alto, CaliforniaAges 10–17 - NCT05942430Recruiting
Bone-cartilage transplant for ankle joint cartilage damage
This trial studies an “autologous” transplant, meaning using your own bone and cartilage, to treat painful cartilage damage in the ankle (on the talus). It may help people whose ankle cartilage injury is deep, has not improved with non-surgical care, and meets specific side and health requirements.
Guangzhou, GuangdongAges 18–60 - NCT07639424RecruitingPhase 4
New cartilage regeneration treatment for knee repair
This study tests a new platform to help repair damaged knee cartilage. If your knee has a specific type of cartilage damage, this treatment might help restore function and reduce pain.
Daegu, DaeguAges 19–64 - NCT07575555Recruiting
Lipedema's role in knee arthritis in women
This study compares women with knee arthritis who do or don't have lipedema (a condition causing painful fat buildup, usually in the legs) to understand how lipedema affects knee joint health. Results may help doctors better treat knee arthritis in women with lipedema.
Izmir, İzmirAges 30–65 - NCT07339111RecruitingPhase 3
CARTISTEM vs surgery for knee cartilage damage and osteoarthritis
This trial tests if a cell-based treatment called CARTISTEM can repair knee cartilage better than surgery alone. It involves people with knee osteoarthritis and a cartilage defect, with moderate pain and limited function.
Birmingham, AlabamaAges 18–75
Hear when a new Articular Cartilage Defect trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for articular cartilage defect?
- Yes. Clin2 currently lists 11 recruiting articular cartilage defect studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a articular cartilage defect trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a articular cartilage defect trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.