Pain relief options for women in early labor
Treatments studied
Part of Brain & nervous system clinical trials.
This trial compares two pain relief methods during the first stage of labor: a combination of tramadol and paracetamol given through an IV, versus pethidine given as a shot. The goal is to see which works better and has fewer side effects.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Pregnancy with a single baby (not twins or more) at full term (37 weeks or more).
- In early labor, with at least 4 painful contractions in 30 minutes, and the cervix is dilated 1 cm or less or 50% thinned out.
- Labor started on its own or was induced by doctors.
- No prior cesarean section (C-section).
- No health conditions like heart, liver, or kidney disease, sleep apnea, or severe obesity (BMI 40 or higher).
- No allergy to paracetamol, tramadol, or pethidine.
- Not taking certain medications like anticonvulsants or MAO inhibitors in the last 14 days.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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