Clin2
NCT07839247Possibly a fitRecruiting

Two oral drugs for brain lymphoma in older adults

Primary Central Nervous System Lymphoma (PCNSL)ZanubrutinibLenalidomideFrail Elderly

Treatments studied

Part of Blood & lymphatic, Brain & nervous system, Cancer clinical trials.

This trial tests a combination of two oral medications (zanubrutinib and lenalidomide) for older adults with a certain type of brain lymphoma. The goal is to see if this treatment can help control the disease with manageable side effects.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
33 people
Ages
70 years and older
Study type
Interventional

Who can take part

  • You must be 70 years or older.
  • You must be considered 'frail' based on a standard geriatric assessment (e.g., limitations in daily activities or significant health issues).
  • You must have a specific type of lymphoma (DLBCL) that is only in your brain or spinal cord, and it must be newly diagnosed.
  • You must be able to have a lumbar puncture (a procedure to take a sample of spinal fluid).
  • Your overall health should be generally stable, with acceptable blood counts, liver, kidney, and blood clotting function.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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