Clin2Atlas
AtlasMental health & substance useMental disorders

Anxiety disorders

1SymptomaticAI-generated
Burden-over-time charts — how many people this disease affects and whether that number is rising or falling — are coming to this page. The treatability read, milestones, and live trial pipeline below are current.

Milestones

dot size = significance
199020002010202020251989 — Clomipramine approved (FDA)1991 — Sertraline approved (FDA)1992 — Paroxetine approved (FDA)1993 — Venlafaxine approved (FDA)1994 — Fluvoxamine approved (FDA)2002 — Escitalopram approved (FDA)2004 — Pregabalin approved (FDA)2004 — Duloxetine approved (FDA)
1989: Drug approval — Clomipramine approved (FDA). 1991: Drug approval — Sertraline approved (FDA). 1992: Drug approval — Paroxetine approved (FDA). 1993: Drug approval — Venlafaxine approved (FDA). 1994: Drug approval — Fluvoxamine approved (FDA). 2002: Drug approval — Escitalopram approved (FDA). 2004: Drug approval — Pregabalin approved (FDA). 2004: Drug approval — Duloxetine approved (FDA)

What's being tested now

2001: 2 trials started2005: 2 trials started2006: 2 trials started2009: 1 trials started2012: 3 trials started2013: 3 trials started2014: 2 trials started2015: 4 trials started2016: 7 trials started2017: 3 trials started2018: 14 trials started2019: 18 trials started2020: 32 trials started2021: 57 trials started2022: 78 trials started2023: 156 trials started2024: 403 trials started2025: 641 trials started2026: 607 trials started201020202026641

Trials started per year, stacked by phase (darker = later phase). Source: ClinicalTrials.gov via Clin2, which tracks studies recruiting in recent years — early years undercount.

See all 1802 active Agoraphobia trials on Clin2 →

Related

SchizophreniaBipolar disorderAutism spectrum disordersAttention-deficit/hyperactivity disorderConduct disorderIdiopathic developmental intellectual disabilityOther mental disorders

Burden estimates: IHME Global Burden of Disease Study. Drug indications: ChEMBL (CC BY-SA). Trial data: ClinicalTrials.gov via Clin2. Velocity, acceleration, and turning points are computed by Clin2 — how this page is made. Treatability describes what medicine can do, not what is available everywhere. This page describes populations, not people, and is not medical advice.