Non-melanoma skin cancer (squamous-cell carcinoma)

Trials started per year, stacked by phase (darker = later phase). Source: ClinicalTrials.gov via Clin2, which tracks studies recruiting in recent years — early years undercount.

Most squamous cell carcinomas are treatable and often cured with early surgical removal. Sun protection prevents many cases. However, advanced or metastatic disease is harder to cure, so outcomes depend on early detection. Death rates have been slowly declining in recent years, though precise figures are not available here.

How fast does squamous cell skin cancer typically grow?

It usually grows slowly over months, but some aggressive forms can spread faster. Early detection and treatment are key to preventing deeper invasion or metastasis.

Can squamous cell skin cancer come back after treatment?

Yes, there is a small risk of local recurrence, especially if the initial tumor was large or deep. Regular skin checks help catch any return early.

What happens if squamous cell cancer spreads to lymph nodes?

Spread to lymph nodes makes treatment more complex, often requiring surgery, radiation, or systemic therapy. Cure is still possible but less likely than with localized disease.

Are there new treatments being studied for advanced disease?

Yes, immunotherapy and targeted therapies are being tested in clinical trials. One trial has started in the last five years, but no phase 3 results are available yet.

Does having one squamous cell cancer increase risk of another?

Yes, people who have had one are at higher risk for new skin cancers. Ongoing sun protection and regular dermatology exams are recommended.