Clin2Atlas
AtlasOther conditionsSkin and subcutaneous diseases

Pruritus

1SymptomaticAI-generated
Burden-over-time charts — how many people this disease affects and whether that number is rising or falling — are coming to this page. The treatability read, milestones, and live trial pipeline below are current.

Milestones

dot size = significance
199020002010202020251993 — Loratadine approved (FDA)1994 — Pheniramine approved (FDA)1995 — Cetirizine approved (FDA)1996 — Olopatadine approved (FDA)2003 — Sertaconazole approved (FDA)2005 — Tetracaine approved (FDA)2006 — Zinc oxide approved (FDA)2008 — Menthol approved (FDA)2009 — Bepotastine approved (FDA)2013 — Luliconazole approved (FDA)2021 — Maralixibat approved (FDA)2021 — Odevixibat approved (FDA)2021 — Difelikefalin approved (FDA)
1993: Drug approval — Loratadine approved (FDA). 1994: Drug approval — Pheniramine approved (FDA). 1995: Drug approval — Cetirizine approved (FDA). 1996: Drug approval — Olopatadine approved (FDA). 2003: Drug approval — Sertaconazole approved (FDA). 2005: Drug approval — Tetracaine approved (FDA). 2006: Drug approval — Zinc oxide approved (FDA). 2008: Drug approval — Menthol approved (FDA). 2009: Drug approval — Bepotastine approved (FDA). 2013: Drug approval — Luliconazole approved (FDA). 2021: Drug approval — Maralixibat approved (FDA). 2021: Drug approval — Odevixibat approved (FDA). 2021: Drug approval — Difelikefalin approved (FDA)

What's being tested now

2013: 1 trials started2020: 1 trials started2021: 2 trials started2022: 3 trials started2023: 7 trials started2024: 11 trials started2025: 27 trials started2026: 26 trials started2020202627

Trials started per year, stacked by phase (darker = later phase). Source: ClinicalTrials.gov via Clin2, which tracks studies recruiting in recent years — early years undercount.

See all 73 active Itching trials on Clin2 →

Related

PsoriasisScabiesFungal skin diseasesViral skin diseasesAcne vulgarisAlopecia areataUrticariaDecubitus ulcerOther skin and subcutaneous diseases

Burden estimates: IHME Global Burden of Disease Study. Drug indications: ChEMBL (CC BY-SA). Trial data: ClinicalTrials.gov via Clin2. Velocity, acceleration, and turning points are computed by Clin2 — how this page is made. Treatability describes what medicine can do, not what is available everywhere. This page describes populations, not people, and is not medical advice.