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Urticaria

1SymptomaticAI-generated
Burden-over-time charts — how many people this disease affects and whether that number is rising or falling — are coming to this page. The treatability read, milestones, and live trial pipeline below are current.

Milestones

dot size = significance
199020002010202020251993 — Loratadine approved (FDA)1995 — Cetirizine approved (FDA)1996 — Fexofenadine approved (FDA)2001 — Desloratadine approved (FDA)2001 — Anakinra approved (FDA)2003 — Omalizumab approved (FDA)2007 — Levocetirizine approved (FDA)2008 — Rilonacept approved (FDA)2008 — Icatibant approved (FDA)2009 — Ecallantide approved (FDA)2009 — Canakinumab approved (FDA)2010 — Conestat alfa approved (FDA)2011 — Human c1-esterase inhibitor approved (FDA)2018 — Lanadelumab approved (FDA)2020 — Berotralstat approved (FDA)
1993: Drug approval — Loratadine approved (FDA). 1995: Drug approval — Cetirizine approved (FDA). 1996: Drug approval — Fexofenadine approved (FDA). 2001: Drug approval — Desloratadine approved (FDA). 2001: Drug approval — Anakinra approved (FDA). 2003: Drug approval — Omalizumab approved (FDA). 2007: Drug approval — Levocetirizine approved (FDA). 2008: Drug approval — Rilonacept approved (FDA). 2008: Drug approval — Icatibant approved (FDA). 2009: Drug approval — Ecallantide approved (FDA). 2009: Drug approval — Canakinumab approved (FDA). 2010: Drug approval — Conestat alfa approved (FDA). 2011: Drug approval — Human c1-esterase inhibitor approved (FDA). 2018: Drug approval — Lanadelumab approved (FDA). 2020: Drug approval — Berotralstat approved (FDA)

What's being tested now

2008: 1 trials started2010: 1 trials started2016: 1 trials started2018: 1 trials started2020: 1 trials started2021: 3 trials started2022: 5 trials started2023: 5 trials started2024: 12 trials started2025: 34 trials started2026: 35 trials started20102020202635

Trials started per year, stacked by phase (darker = later phase). Source: ClinicalTrials.gov via Clin2, which tracks studies recruiting in recent years — early years undercount.

See all 85 active Angioedema trials on Clin2 →

Related

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Burden estimates: IHME Global Burden of Disease Study. Drug indications: ChEMBL (CC BY-SA). Trial data: ClinicalTrials.gov via Clin2. Velocity, acceleration, and turning points are computed by Clin2 — how this page is made. Treatability describes what medicine can do, not what is available everywhere. This page describes populations, not people, and is not medical advice.