Blood test guides extra treatment after stage II colon cancer surgery
Treatments studied
Part of Cancer, Digestive system clinical trials.
This study uses a blood test called ctDNA to decide whether you need extra (adjuvant) chemotherapy after stage II colon or certain stage II rectal cancer surgery. It may help avoid unnecessary treatment or better target people who still have signs of cancer after surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You had colon cancer stage II surgery, or rectal cancer stage II surgery, with no need for radiotherapy
- You can join the initial screening and sign consent for the screening phase
- Your tumor’s DNA repair pattern is known (microsatellite status or mismatch repair status)
- Your ctDNA test result is available
- You can sign a second consent for the randomized treatment phase
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial is for people with stage II colon cancer who are not currently getting chemotherapy. It uses a blood test to look for tumor DNA, so doctors can decide if chemotherapy might help prevent the cancer from coming back.
This study helps doctors decide whether you need chemotherapy after colon cancer surgery by checking for cancer DNA in your blood. The goal is to give chemotherapy only to patients who truly need it, based on what the blood test shows.
This study uses a simple blood test to detect cancer DNA after surgery for early-stage colon cancer. The goal is to help doctors decide whether chemotherapy is truly needed based on the blood test results, rather than giving it to everyone.
This study tests whether giving additional (adjuvant) chemotherapy based on a special blood test—circulating tumor DNA (ctDNA)—can lower the risk of colon cancer coming back. It targets people with stage II–III colon cancer whose blood test is positive for minimal residual disease (MRD) after completing standard chemo.
This trial tests whether a blood test that looks at cancer DNA can help decide whether you need “adjuvant” (extra) chemotherapy after colon cancer surgery. It may help some patients avoid unnecessary chemotherapy while still keeping the cancer from coming back.
This study uses a blood test to check for tumor DNA after surgery, which may help doctors decide if you need additional chemotherapy. It is for people with stage 3 colorectal cancer that is removed by surgery.
Hear when a new Colon Cancer Stage II trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.