Clin2
NCT06524323Possibly a fitNot yet recruiting

Injection treatment for stubborn nodular prurigo

Nodular Prurigo

Treatments studied

Part of Skin clinical trials.

This trial tests if a combination injection of two drugs (5-fluorouracil and triamcinolone) can clear stubborn nodules that haven't responded to other treatments. It may help people with long-lasting, itchy bumps that are hard to treat.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
60 people
Ages
18 years to 70 years
Study type
Interventional

Who can take part

  • You have had nodular prurigo (itchy bumps) for at least 6 months
  • You have 10 to 12 symmetrically distributed bumps on your trunk or limbs
  • You have tried other treatments (like antihistamines or special medications) but they only partly helped
  • You haven't had this specific injection in the past 12 weeks
  • You are between 18 and 70 years old
  • You agree to use birth control if needed during the trial and for 6 months after

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06554509Recruiting· Phase 2/Phase 3
Study of SHR-1819 for prurigo nodularis

This trial tests an injection called SHR-1819 for adults with prurigo nodularis, a skin condition with itchy bumps. The goal is to see if it helps reduce itching and bumps.

Beijing, Beijing Municipality
NCT07236099Recruiting· Phase 2
Study of ICP-332 for prurigo nodularis

This trial tests an experimental drug called ICP-332 for people with prurigo nodularis (a condition causing very itchy, hard bumps on the skin). It aims to see if the drug can safely reduce itching and improve skin lesions.

Birmingham, Alabama
NCT06779136Recruiting· Phase 3
Study of MG-K10 for prurigo nodularis

This trial tests an investigational drug called MG-K10 for people with prurigo nodularis, a skin condition that causes intense itching and bumps. The goal is to see if it can help reduce itch and improve skin.

Beijing, Bejing
NCT06293053Recruiting· Phase 3
Study of Dupilumab in children with prurigo nodularis

This trial tests a new medicine (Dupilumab) for children with a severe itchy skin condition called prurigo nodularis. It aims to see if the treatment is safe and how it works in the body.

Palo Alto, California
NCT06988618Recruiting
Real-world use of nemolizumab for adults with prurigo nodularis

This study looks at how well nemolizumab works in real-world settings for adults with moderate-to-severe prurigo nodularis, a skin condition that causes intense itching and bumps. If you are starting this medication as part of your normal care, you may be able to join.

Birmingham, Alabama
NCT07620561Not yet recruiting· Phase 2
Lebrikizumab for severe itching and bumps in prurigo nodularis

This study tests whether a drug called lebrikizumab can reduce severe itching and skin bumps caused by prurigo nodularis (a chronic skin condition). The drug works by calming an overactive immune response in the skin.

Baltimore, Maryland

Hear when a new Nodular Prurigo trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.