Managing mild diverticulitis without antibiotics
Treatments studied
Part of Digestive system clinical trials.
This study tests whether some patients with mild diverticulitis (inflammation in the colon) can recover without antibiotics, using rest and supportive care instead. If it works, it could help avoid unnecessary antibiotics and their side effects.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Confirmed left-sided diverticulitis on CT scan that is mild (no pockets of infection, holes, or air leakage)
- White blood cell count under 15,000 per milliliter of blood
- Pain controlled (score below 5 on a 0–10 scale) and able to eat or drink by mouth
- No fever or signs of serious infection like sepsis
- Not currently taking or recently took antibiotics in the past 2 weeks
- No complicated diverticulitis, weakened immune system, inflammatory bowel disease, or serious health conditions
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether antibiotics are necessary for mild diverticulitis or if a placebo works just as well. Participants are treated in the emergency department and followed using a smartphone app.
This trial tests if mild diverticulitis (a small infection in the colon) can be safely treated at home without antibiotics. If you have this condition and are otherwise healthy, you may be able to avoid a hospital stay.
This trial compares two treatments for a diverticulitis complication where a pus-filled pocket (abscess) forms near the colon. You either receive antibiotics alone or a procedure to drain the abscess, and researchers will see which leads to better outcomes.
This trial compares non-operative management for acute left colonic diverticulitis (ALCD) in medical versus surgical wards, to see which setting leads to better outcomes. If you have diverticulitis diagnosed by CT scan and are being treated without immediate surgery, you may be eligible.
This trial tests MBK-01, capsules made from healthy gut bacteria, to see if they can help people who keep getting diverticulitis. If you've had three or more bouts in the last three years, this study might offer a new treatment option.
This study looks at how the bacteria in your gut might be related to diverticular disease (pouches in your colon). If you have had diverticulitis, researchers want to see if your gut microbiome is different from people without the condition.
Hear when a new Acute Uncomplicated Diverticulitis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.