Clinical trials
Acne clinical trials
Below are recruiting acne clinical trials, each written for real people, not researchers. We’re tracking 48 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06316297RecruitingPhase 1/Phase 2
Testing a new mRNA vaccine for moderate to severe acne
This study tests an experimental mRNA vaccine designed to help the immune system fight acne-causing bacteria. It's for adults with moderate or severe facial acne who are otherwise healthy, and it may offer a new way to treat acne beyond typical creams or pills.
Scottsdale, ArizonaAges 18–45 - NCT07013747RecruitingPhase 1/Phase 2
Acne mRNA vaccine for mild acne
This trial tests an mRNA vaccine designed to treat mild facial acne. It aims to see if the vaccine is safe and effective at reducing acne lesions.
Encino, CaliforniaAges 18–45 - NCT03465150Recruiting
People with acne can join an acne patient study
This study creates a group (cohort) of patients treated for acne at a hospital to better understand acne care in real life. It may help improve future care by sharing what treatments people receive and how they do over time.
NantesAges Any age - NCT06311890RecruitingPhase 2
Light therapy for moderate to severe acne
This trial tests a light-activated therapy (called photodynamic therapy) using a special gel that is put on the skin and then activated with a light to treat moderate to severe acne. It may help people who have not responded well to other treatments.
BeijingAges 18–50 - NCT06463925Recruiting
Acne cream for face and trunk acne
This study tests a new acne cream (Effaclar Duo+M) for people with mild to moderate acne on their face and trunk. It aims to see if the cream helps clear acne and is gentle on the skin.
Rio de JaneiroAges 18 years+ - NCT07056673Recruiting
Cold plasma for moderate to severe acne
This study tests whether a treatment called 'cold atmospheric plasma' (similar to a gentle, cool gas) can improve moderate-to-severe acne. It might offer a new, drug-free option for people with many pimples or cysts.
Luoyang, HenanAges 18–40 - NCT05362929Recruiting
Laser treatment for acne scars in darker skin tones
This study tests a new type of laser treatment for acne scars in people with darker skin tones. It aims to see if the laser is effective and safe for improving the appearance of scars.
Elmsford, New YorkAges 18 years+ - NCT07749469Recruiting
Soothing skincare for mild to moderate acne in sensitive skin
This trial tests skincare products designed for people with sensitive skin who have mild to moderate acne. The goal is to see if they safely and effectively reduce acne without irritating sensitive skin.
Petaling Jaya, SelangorAges 18 years+ - NCT04028401RecruitingPhase 3
Skin prep study to reduce bacteria in shoulder replacement surgery
This study tests whether a specific skin-cleaning method before shoulder replacement surgery can reduce a common bacteria (Cutibacterium acnes) found on skin and deeper samples. It may help lower the risk of infection or contamination during prosthetic shoulder surgery.
AngersAges 18 years+ - NCT06978361Recruiting
Microneedling with PRP vs insulin for acne scars
This trial compares two treatments for acne scars: microneedling combined with platelet-rich plasma (PRP), versus microneedling combined with insulin. The goal is to see which works better for improving scar appearance.
Peshawar, KPK ,PakistanAges 18–50 - NCT07352215Recruiting
Platelet-rich plasma plus CO2 laser for acne scars
This study tests whether combining your own blood proteins (PRP) with a fractional CO2 laser can improve moderate-to-severe acne scars more than laser alone. You would have 3 treatment sessions spaced several weeks apart.
Gujranwala, Punjab ProvinceAges 18–40 - NCT06544993Recruiting
Microneedling with Botox vs Meso-Botox for acne scars
This study compares two treatments for sunken acne scars on the face: microneedling combined with Botox versus a 'meso-Botox' injection. Each side of your face gets one treatment, so doctors can see which works better for you.
SohagAges 18–50 - NCT06831422Recruiting
Antimicrobial Wash During Shoulder Replacement
This study tests whether washing the surgical site with a special antimicrobial liquid after the incision can lower the risk of infection during shoulder replacement surgery. It may help people who are already planning a first-time shoulder replacement.
Detroit, MichiganAges 18 years+ - NCT07207369RecruitingPhase 3
Study of an injectable gel for atrophic acne scars
This study tests an injectable gel called ELAPR002f for treating moderate to severe atrophic acne scars on the cheeks. If you have rolling or boxcar scars and are in good general health without active acne or other skin issues, this trial may help improve your scars.
Glendale, ArizonaAges 22 years+ - NCT07547956Recruiting
Two injection treatments for rolling acne scars
This study compares two different injectable treatments for deep, rolling acne scars. Half of your face will receive one type of injection and the other half will receive a different type, to see which works better at smoothing out scarring.
CairoAges 18 years+ - NCT07523217Recruiting
Poly-L-Lactic Acid Treatment for Depressed Acne Scars
This trial tests whether injections of poly-L-lactic acid (a safe, absorbable filler material) can improve the appearance of depressed or pitted acne scars. If it works, it may offer patients a non-surgical way to smooth out and reduce the visibility of these scars.
Zagazig, Sharqia ProvinceAges 18–40 - NCT07151599Recruiting
Comparing lasers and microneedling for acne scars
This study compares three types of treatments — two lasers and microneedling — to improve depressed acne scars on the face. It is for people with a range of skin tones who have not had recent facial treatments or used certain medications.
São PauloAges 18–45 - NCT03883269RecruitingPhase 4
Tests topical antibiotics’ anti-inflammatory effect in acne
This trial studies whether putting antibiotic creams on mild-to-moderate facial acne reduces inflammation. It may help answer whether topical erythromycin or clindamycin can improve acne-related redness and swelling.
LeidenAges 18–45 - NCT05942248Recruiting
Computer image grading for common face skin rashes
This study uses special computer measurements from facial photos to evaluate how acne, rosacea, melasma, or seborrheic dermatitis look. If you have one of these conditions, it may help researchers better track skin changes over time.
Sacramento, CaliforniaAges 18 years+ - NCT06225570RecruitingEarly Phase 1
Weekly isotretinoin vs tetracycline for moderate acne
This trial tests a weekly dose of isotretinoin (a strong acne medicine) versus a standard tetracycline antibiotic for treating moderate acne. It aims to find a simpler, effective option with fewer side effects.
Charleston, South CarolinaAges 12 years+ - NCT06403501RecruitingPhase 3
Clascoterone cream for facial acne
This trial tests a new cream called clascoterone for moderate to severe facial acne. It may help reduce pimples and blackheads with fewer side effects than some other treatments.
ShanghaiAges 12 years+ - NCT06447480RecruitingPhase 3
Comparing isotretinoin to standard care for moderate acne in darker skin
This trial compares oral isotretinoin (a strong acne medication) to standard treatments for people with moderate acne and darker skin tones. It aims to find which treatment works best for skin of color.
Nice, Alpes-MaritimesAges 13–30 - NCT06501560Recruiting
Acne genetics study in Indonesia
This study looks at genetic patterns in young people with acne in Indonesia. It aims to better understand why some people get acne, which may help improve future treatments.
Jakarta Pusat, Jakarta Special Capital RegionAges 17–60 - NCT06716398Recruiting
A cosmetic study for teens and young adults with acne
This study tests a cosmetic product alongside a standard prescription acne treatment for 12 weeks, then a maintenance phase to see if the product helps improve acne and skin appearance.
São PauloAges 14–24
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Acne trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for acne?
- Yes. Clin2 currently lists 48 recruiting acne studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a acne trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a acne trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.