Clinical trials
Acne clinical trials
Below are recruiting acne clinical trials, each written for real people, not researchers. We’re tracking 51 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07013747RecruitingPhase 1/Phase 2
Acne mRNA vaccine for mild acne
This trial tests an mRNA vaccine designed to treat mild facial acne. It aims to see if the vaccine is safe and effective at reducing acne lesions.
Encino, CaliforniaAges 18–45 - NCT06316297RecruitingPhase 1/Phase 2
Testing a new mRNA vaccine for moderate to severe acne
This study tests an experimental mRNA vaccine designed to help the immune system fight acne-causing bacteria. It's for adults with moderate or severe facial acne who are otherwise healthy, and it may offer a new way to treat acne beyond typical creams or pills.
Scottsdale, ArizonaAges 18–45 - NCT07056673Recruiting
Cold plasma for moderate to severe acne
This study tests whether a treatment called 'cold atmospheric plasma' (similar to a gentle, cool gas) can improve moderate-to-severe acne. It might offer a new, drug-free option for people with many pimples or cysts.
Luoyang, HenanAges 18–40 - NCT06905210RecruitingPhase 3
New hormonal pill for moderate acne in women
This trial tests a new combination hormonal pill (a progestogen and low-dose estrogen) to treat moderate acne in women. It may be an option if you have not had success with other acne treatments.
Itapevi, São PauloAges 14–45 - NCT03465150Recruiting
People with acne can join an acne patient study
This study creates a group (cohort) of patients treated for acne at a hospital to better understand acne care in real life. It may help improve future care by sharing what treatments people receive and how they do over time.
NantesAges Any age - NCT03883269RecruitingPhase 4
Tests topical antibiotics’ anti-inflammatory effect in acne
This trial studies whether putting antibiotic creams on mild-to-moderate facial acne reduces inflammation. It may help answer whether topical erythromycin or clindamycin can improve acne-related redness and swelling.
LeidenAges 18–45 - NCT07863193RecruitingPhase 3
Denifanstat for moderate to severe acne
This trial tests an experimental pill called denifanstat to see if it can clear up moderate to severe acne. If you qualify, you may receive the study drug or a placebo, and researchers will check how well it works on your skin over time.
Bryant, ArkansasAges 12 years+ - NCT07866131Recruiting
Observational study of PRX S cosmetic treatment for acne-prone skin
This study looks at how a cosmetic treatment called PRX S affects the appearance of acne-prone skin. You would receive 5 treatment sessions over about 8 weeks and use only the provided skincare products during the study.
Leawood, KansasAges 18 years+ - NCT07834138Recruiting
Study of facial skin bacteria in acne patients treated with isotretinoin
This study looks at how the bacteria on your face change when you take a medicine called isotretinoin for acne. It might help doctors understand why the medicine works and how to improve acne treatment.
Can ThoAges 16–35 - NCT07818525Recruiting
Hormone levels and response to isotretinoin for acne in women
This study looks at how a woman's natural hormone levels affect how well she responds to isotretinoin (a strong acne pill). It aims to help doctors predict which patients will benefit most from this treatment.
Küçükçekmece, IstanbulAges 18–40 - NCT07822360Recruiting
Acne and hormonal imbalance risk in young women
This study looks at how common polyendocrine metabolic ovarian syndrome (PMOS), a hormonal condition, is in women with acne. It aims to find if acne could be a sign of this condition, which might help with early detection and treatment.
SohagAges 15–49 - NCT07805655Recruiting
Radiofrequency vs. topical therapy for facial acne
This study compares a radiofrequency treatment to a topical cream for facial acne. It aims to see which is more effective for mild to moderate acne in adults.
Nuevo León, MonterreyAges 18–40 - NCT07749469Recruiting
Soothing skincare for mild to moderate acne in sensitive skin
This trial tests skincare products designed for people with sensitive skin who have mild to moderate acne. The goal is to see if they safely and effectively reduce acne without irritating sensitive skin.
Petaling Jaya, SelangorAges 18 years+ - NCT06716398Recruiting
A cosmetic study for teens and young adults with acne
This study tests a cosmetic product alongside a standard prescription acne treatment for 12 weeks, then a maintenance phase to see if the product helps improve acne and skin appearance.
São PauloAges 14–24 - NCT07544251RecruitingPhase 4
Sarecycline vs. Doxycycline for Acne and Gut Health
This study compares two antibiotic medications (sarecycline and doxycycline) to see which one works better for moderate acne while also being gentler on the bacteria in your gut. Researchers will track how your skin improves and how these drugs affect your digestive system.
Sacramento, CaliforniaAges 9 years+ - NCT07547956Recruiting
Two injection treatments for rolling acne scars
This study compares two different injectable treatments for deep, rolling acne scars. Half of your face will receive one type of injection and the other half will receive a different type, to see which works better at smoothing out scarring.
CairoAges 18 years+ - NCT07523217Recruiting
Poly-L-Lactic Acid Treatment for Depressed Acne Scars
This trial tests whether injections of poly-L-lactic acid (a safe, absorbable filler material) can improve the appearance of depressed or pitted acne scars. If it works, it may offer patients a non-surgical way to smooth out and reduce the visibility of these scars.
Zagazig, Sharqia ProvinceAges 18–40 - NCT07474883RecruitingEarly Phase 1
Timolol eye drops for red marks after acne
This trial tests if timolol eye drops, applied to the skin, can reduce red marks left by acne. It may be an option for people with acne-related redness who haven't responded to other treatments.
Ho Chi Minh CityAges 12 years+ - NCT07366229RecruitingPhase 2
Friendly bacteria cream for mild to moderate acne
This trial tests a special cream made from a friendly bacteria (Lactobacillus) that is coated to help it stick to the skin. It is for people with mild to moderate acne who have not taken other acne treatments recently.
Shenzhen, GuangdongAges 18–33 - NCT07352215Recruiting
Platelet-rich plasma plus CO2 laser for acne scars
This study tests whether combining your own blood proteins (PRP) with a fractional CO2 laser can improve moderate-to-severe acne scars more than laser alone. You would have 3 treatment sessions spaced several weeks apart.
Gujranwala, Punjab ProvinceAges 18–40 - NCT07296523Enrolling by invitation
Expert views on isotretinoin for acne
This study gathers opinions from experienced dermatologists to create expert guidelines on using isotretinoin for acne. It does not test a new treatment but aims to improve how isotretinoin is prescribed.
CairoAges Any age - NCT07239349Recruiting
Acne face wash to reduce shoulder surgery infection risk
This study tests whether using a special acne face wash before shoulder surgery can lower the risk of infection. If you have a rotator cuff tear and are scheduled for arthroscopic repair, you may be able to join.
TaipeiAges 18 years+ - NCT07207369RecruitingPhase 3
Study of an injectable gel for atrophic acne scars
This study tests an injectable gel called ELAPR002f for treating moderate to severe atrophic acne scars on the cheeks. If you have rolling or boxcar scars and are in good general health without active acne or other skin issues, this trial may help improve your scars.
Glendale, ArizonaAges 22 years+ - NCT04028401RecruitingPhase 3
Skin prep study to reduce bacteria in shoulder replacement surgery
This study tests whether a specific skin-cleaning method before shoulder replacement surgery can reduce a common bacteria (Cutibacterium acnes) found on skin and deeper samples. It may help lower the risk of infection or contamination during prosthetic shoulder surgery.
AngersAges 18 years+
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Acne trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for acne?
- Yes. Clin2 currently lists 51 recruiting acne studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a acne trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a acne trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.