Clinical trials
Propionic Acidemia clinical trials
Below are recruiting propionic acidemia clinical trials, each written for real people, not researchers. We’re tracking 7 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT02890342Recruiting
Studying Propionic Acidemia, gut bacteria, and body chemistry over time
This study follows people with propionic acidemia to better understand how the body, diet, gut bacteria, and blood chemistry change over time. It may help researchers learn more about the condition and how pregnancy, transplant, and daily life affect health.
Bethesda, MarylandAges 1 month–100 years - NCT04159103RecruitingPhase 1/Phase 2
mRNA treatment for propionic acidemia, tested in a study
This trial tests an mRNA medicine (mRNA-3927) in people with propionic acidemia (PA). It aims to see whether this treatment is safe and can help the body when PA is confirmed by genetic testing.
Los Angeles, CaliforniaAges Any age - NCT05769621Recruiting
Study of medical records in propionic acidemia patients
This is a “chart review” study that looks at how people with propionic acidemia have symptoms and medical events over time. It uses existing medical records (not an experimental drug) to better understand the disease and care needs.
Stanford, CaliforniaAges 2 years+ - NCT07643844RecruitingPhase 1
Gene therapy for propionic acidemia in infants
This trial tests a new gene therapy treatment designed to help the body process certain amino acids better in infants with propionic acidemia. The therapy uses a modified virus to deliver a working copy of a faulty gene, potentially reducing dangerous acid buildups and hospital visits.
Rochester, MinnesotaAges 6 months–2 years - NCT04176523Recruiting
Study of long-term carglumic acid use in organic acidemia
This study looks at how people with organic acidemia (like MMA or PA) do over the long term while taking carglumic acid. The research may help improve long-term management and support for patients and caregivers.
BordeauxAges 6 months–99 years - NCT05040178Recruiting
Study of Carbaglu® use for MMA and PA
This observational study looks at how Carbaglu® is used and how well it works for people with methylmalonic acidemia (MMA) or propionic acidemia (PA). It may help doctors understand real-world care for adults and children living with these conditions.
Washington D.C., District of ColumbiaAges Any age - NCT05130437RecruitingPhase 1/Phase 2
Follow-up study for an mRNA vaccine given before
This is a follow-up study for people who already received the mRNA-3927 vaccine in an earlier trial. It looks at how safe the treatment is over the long term and whether it continues to have benefit.
Los Angeles, CaliforniaAges 1 year+
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Propionic Acidemia trials by city
Studies with a site in or near these metro areas.
Propionic Acidemia trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for propionic acidemia?
- Yes. Clin2 currently lists 7 recruiting propionic acidemia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a propionic acidemia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a propionic acidemia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.