Clinical trials
Real World Study clinical trials
Below are recruiting real world study clinical trials, each written for real people, not researchers. We’re tracking 349 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06361589Recruiting
Lorlatinib for advanced ALK-positive lung cancer
This study is testing a targeted therapy called lorlatinib in people with advanced ALK-positive lung cancer. It aims to see how well this oral medication works in a real-world setting.
Chengdu, SichuanAges 18 years+ - NCT07566559Recruiting
Rectal Cancer Treatment Before Surgery Study
This study follows real-world treatment of locally advanced rectal cancer (cancer that has grown into nearby tissues but hasn't spread to distant organs) in patients who receive chemotherapy and/or radiation before surgery. Researchers track how different treatment approaches work to help improve outcomes.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07374614Recruiting
Study of iruplinalkib after lorlatinib for ALK-positive lung cancer
This trial is for people with advanced lung cancer whose tumors have an ALK gene change and who have already taken a medicine called lorlatinib. It tests a new drug, iruplinalkib, to see how well it works for those who stopped responding to or couldn't tolerate lorlatinib.
Shenzhen, GuangdongAges 18 years+ - NCT07279402Recruiting
Real-world study of atezolizumab for advanced lung cancer
This trial looks at how well atezolizumab works for people with stage IV non-small cell lung cancer that has a high level of PD-L1 (a protein that helps cancer hide from the immune system). It's for people getting atezolizumab as their first treatment.
AdanaAges 18 years+ - NCT07165717Recruiting
Real-world study of breathing emergencies in ICU patients
This study looks at why some patients develop severe breathing problems in the ICU. It focuses on people who already have conditions like severe infections, injuries, or heavy bleeding that can stress the lungs.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07117227Recruiting
Study to test a kidney cancer prediction model
This study is checking how well a model can predict the outcomes for people with kidney cancer who have had surgery. It looks at your medical records after surgery to help doctors better understand your recovery and future risks.
Beijing, Beijing MunicipalityAges 18–80 - NCT06726720Recruiting
Real-world study of approved lung cancer drugs
This study looks at how well approved AstraZeneca drugs work for non-small cell lung cancer in everyday medical practice. It does not test new treatments, but gathers information to help doctors and patients make better decisions.
Aix-en-ProvenceAges 18 years+ - NCT05570149Recruiting
Study of eptinezumab in people with frequent migraine
This real-world study looks at how well eptinezumab (an antibody medicine for migraine prevention) works for people with frequent episodic or chronic migraine as they get usual care. You may be asked to share health information and treatment details to see what helps most in everyday life.
Roma, RMAges 18–75 - NCT05391815Recruiting
Observational study of endovascular treatment for blocked leg arteries
This is a real-world observational study that follows people who get minimally invasive procedures to treat blocked arteries in the lower abdomen and pelvis. It aims to understand how well these treatments work in the middle and long term.
ShanghaiAges 18–80 - NCT07874451Recruiting
Study of BCL-2 inhibitor treatments for chronic lymphocytic leukemia
This study looks at real-world experiences of people with chronic lymphocytic leukemia (CLL) who have used or are using a type of targeted therapy called a BCL-2 inhibitor. It aims to understand how well these treatments work and their side effects in everyday practice.
Nanjing, JiangsuAges 18 years+ - NCT04025944Recruiting
Study of long-term hepatitis B or C infection
This study looks at people with hepatitis B or C infections that have lasted more than 6 months. It aims to better understand long-term management and how treatments may help over time.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT04037995Recruiting
Real-world study of advanced liver disease in China
This study looks at people with very advanced liver problems to better understand what happens in real life. It may help doctors improve care for advanced cirrhosis and certain liver cancers.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT04286841Recruiting
Immunotherapy before lung surgery for early lung cancer
This trial looks at giving immunotherapy before surgery for certain early-stage lung cancers to help shrink the tumor and improve outcomes. It is mainly for people whose lung cancer can be removed by surgery and who don’t have specific gene changes like EGFR or ALK.
Guangzhou, GuangdongAges 18 years+ - NCT04020536Recruiting
Real-world study for several infectious diseases
This study follows people with confirmed brucellosis, epidemic hemorrhagic fever, or kala-azar (visceral leishmaniasis) to understand how these infections behave in real life. It may help improve care by collecting evidence on diagnosis and treatment outcomes.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT05387369Recruiting
Real-world study of Paxlovid for hospitalized COVID-19 patients
This study checks how Paxlovid works in everyday care for people who are hospitalized with confirmed COVID-19. If you have a positive COVID-19 test and mild to moderate symptoms, this trial may help doctors understand how well the treatment performs outside of tightly controlled settings.
ShanghaiAges 12 years+ - NCT05498064Recruiting
Study of ensartinib for advanced ALK-positive lung cancer
This real-world study looks at how ensartinib works in people with advanced ALK-positive non-small cell lung cancer (NSCLC) whose disease has continued or worsened after ALK-targeted therapy. It may help doctors understand how well the treatment works and who benefits most in everyday care.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05846763Recruiting
Obinutuzumab plus lenalidomide for returning follicular lymphoma
This study looks at giving obinutuzumab together with lenalidomide to adults whose follicular lymphoma has come back or did not respond well to prior treatment. It may help control the cancer after relapse or resistance to standard therapies.
TianjinAges 18 years+ - NCT05899621Recruiting
Study of obinutuzumab-based treatment for untreated follicular lymphoma
This real-world study looks at how well obinutuzumab-based treatment works for people with newly diagnosed follicular lymphoma. It is meant for patients whose cancer is measurable on scans and who are eligible for specific standard treatment combinations.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT05937178Recruiting
Real-World Study to Optimize Hepatitis B Tablet Treatment
This study looks at how to best use existing hepatitis B “nucleotide-analog” tablets in everyday care. It may help tailor when to start, and whether to continue or adjust treatment, based on your test results.
Hefei, AnhuiAges 18–80 - NCT06216782Recruiting
Neoadjuvant therapy for lung cancer: a real-world study
This study observes patients with lung cancer who receive neoadjuvant therapy (treatment before surgery) to understand how well it works in everyday medical practice.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07874308Recruiting
Preventing nausea and vomiting from chemotherapy
This study tests a new anti-nausea drug (HR20013) in patients receiving chemotherapy that often causes nausea and vomiting. It aims to see how well it works in real-world conditions, including for patients with liver problems.
Guangzhou, GuangdongAges 18 years+ - NCT07823465Enrolling by invitation
Brain device study for teens with focal epilepsy
This study looks at how well an implanted brain device works for teenagers with focal epilepsy that doesn't improve with medicine. The device sends small electrical pulses to specific brain areas to reduce seizures, and this study will help learn if it's safe and helpful for teens.
Waltham, MassachusettsAges 13–19 - NCT06485271Recruiting
Camrelizumab for advanced gastric cancer
This trial tests a drug called camrelizumab, alone or with other treatments, for people with advanced stomach cancer that has worsened or returned. It aims to see how well this treatment works in real-world patients.
Changzhi, ShanxiAges 18–75 - NCT07806604Recruiting
Icotinib after surgery for early lung cancer with EGFR mutation
This trial studies a pill called icotinib, given after lung cancer surgery, to see if it helps prevent the cancer from returning in people with early-stage, EGFR-mutant non-small cell lung cancer. It is a real-world study, meaning it looks at how the treatment works in routine practice.
Beijing, Beijing MunicipalityAges 18 years+
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Common questions
- Are there clinical trials for real world study?
- Yes. Clin2 currently lists 349 recruiting real world study studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a real world study trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a real world study trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.