Test ALK-001 for Stargardt disease eye changes and comfort
Part of Eyes & vision, Genetic & congenital clinical trials.
This Phase 2 study tests how well ALK-001 is tolerated and whether it can slow or improve vision-related changes in people with Stargardt disease. It mainly looks at safety (tolerability) and signs in the eye over about 24 months.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be between 8 and 70 years old, inclusive
- Have a confirmed diagnosis of Stargardt disease type 1 caused by ABCA4 gene changes
- Have at least one ABCA4 mutation (or, if only one is found, the study must approve)
- Have a study eye with visible retina changes on special eye scans and tests (or changes expected to worsen during the study)
- Be able to take part in 24 months of study visits and tests, including eye-dilation drops
- Agree to the study by signing informed consent (or assent if a child) and follow pregnancy-prevention rules if needed
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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