Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,762 recruiting studies in this area right now.
By phase
- Not applicable1,204
- Phase 3131
- Phase 2119
- Phase 1117
- Phase 492
- Phase 1/Phase 285
- Phase 2/Phase 314
Top conditions
- Glaucoma107
- Myopia88
- Cataract76
- Diabetic Retinopathy51
- Dry Eye38
- Keratoconus34
- Retinitis Pigmentosa33
- Age-Related Macular Degeneration31
- Amblyopia26
- Eye Diseases24
- Graves Disease24
- Sjogren's Syndrome24
- Dry Eye Disease (DED)23
- Multiple Sclerosis22
- Astigmatism21
- Ocular Hypertension21
- Diabetic Macular Edema20
- Macular Degeneration20
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University25
- Medical University of Vienna20
- Second Affiliated Hospital, Zhejiang University, School of Medicine19
- Fondation Ophtalmologique Adolphe de Rothschild18
- Assistance Publique - Hôpitaux de Paris16
- National Taiwan University Hospital16
- The Hong Kong Polytechnic University16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
Where studies are running
- California132
- Arizona68
- Florida42
- Maryland39
- Texas38
- New York36
- Massachusetts35
- Alabama26
- North Carolina20
- Pennsylvania20
Recruiting studies1,762 total
- NCT06321302RecruitingPhase 2
Study of BI 764524 for diabetic retinopathy
This study tests an investigational drug called BI 764524 for people with moderate to severe diabetic retinopathy, a complication of diabetes that can damage the retina. The goal is to see if the treatment can help prevent vision loss.
Phoenix, ArizonaAges 18 years+ - NCT05805007RecruitingEarly Phase 1
Gene editing treatment for retinitis pigmentosa
This study tests a gene-editing drug, ZVS203e, injected into one eye to see if it is safe and tolerable for people with retinitis pigmentosa caused by a specific genetic change in the RHO gene. It may help slow vision loss or improve vision, but the main goal is to check safety.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07617090Recruiting
Testing progressive glasses for reading and distance in presbyopia
This trial compares two types of progressive glasses to see which works better for seeing at arm's length and up close. It is for people with presbyopia who have relatively mild vision problems.
Seville, AndalusiaAges 52–67 - NCT07298824RecruitingPhase 2
MR-61 eye drops for slowing nearsightedness in children
This trial tests an eye drop called MR-61 to see if it can slow down worsening nearsightedness (myopia) in children and teens. The study aims to find a safe and easy way to keep their vision from getting worse.
Nanchang, JiangxiAges 3–18 - NCT07093255RecruitingPhase 1
Testing FLQ-101 safety in premature babies
This study tests a new medicine called FLQ-101 in very premature babies born between 25 and 27 weeks of pregnancy. The goal is to see if the medicine is safe and how it works in the body.
Austin, TexasAges 4 days–5 days - NCT07740564RecruitingPhase 3
Study of an eye drop for moderate to severe dry eye
This study tests an investigational eye drop called OT202 to see if it helps people with moderate to severe dry eye. If you join, you'll receive either the study drug or a placebo (no active ingredient) and have your symptoms and eye health monitored for several months.
Bengbu, AnhuiAges 30–75 - NCT07637500Recruiting
Tiny Eye Insert to Improve Close-up Vision
This trial tests a tiny device inserted into the eye to help people aged 45–60 who have trouble seeing up close. If you have good distance vision but struggle reading or seeing near objects, this study may help you see better without glasses for reading.
BochumAges 45–60 - NCT00001373Recruiting
Understanding the genetics of autoinflammatory diseases
This study collects genetic samples and medical histories from people with autoinflammatory diseases (like Familial Mediterranean Fever), their relatives, and healthy volunteers to understand how these conditions run in families and what causes them. Participation mainly involves providing a mail-in DNA sample.
Washington D.C., District of ColumbiaAges 2 months–115 years - NCT07498426RecruitingPhase 3
Study of NIO752 for progressive supranuclear palsy
This trial tests a new medicine called NIO752 for people with progressive supranuclear palsy (PSP), a condition that affects movement, balance, and thinking. The goal is to see if it can help slow the disease's progression.
Scottsdale, ArizonaAges 41–81 - NCT01438658Recruiting
Test blood markers to help diagnose metastatic uveal melanoma
This study checks whether blood “biomarkers” (measurable signs in serum) can help diagnose metastatic uveal melanoma. If you have uveal melanoma, the study may look at how useful these blood tests are for spotting spread to other parts of the body.
JerusalemAges Any age - NCT02485847Recruiting
Join an eye health research registry
This trial is a research registry that collects information from people who are getting eye care. It helps researchers better understand eye disease and outcomes over time, which may improve future care.
San Francisco, CaliforniaAges 6 months+ - NCT03587948Recruiting
Diabetes eye study for teens with diabetes
This study looks at how diabetes affects the eyes in children and teens. It may help doctors better detect or understand eye problems earlier in people with diabetes.
Shanghai, Shanghai MunicipalityAges 5–18 - NCT03473912Recruiting
Rheumatoid disease biobank study for adults
This study asks adults with a rheumatoid condition to join a biobank, which is a safe place to store health information and biological samples for future research. It may help researchers better understand rheumatoid conditions and develop better treatments.
Kfar SabaAges 18–120 - NCT04187599Recruiting
Check how a specific contact lens fits and works
This study follows up on how the Paragon CRT® 100 (paflufocon D) contact lens performs after being used in the real world. It aims to confirm the lens is comfortable and safe for the right eye measurements and health conditions.
ShanghaiAges 8 years+ - NCT04205916RecruitingPhase 4
Preference trial of eye drops versus no-drops after cataract surgery
This trial compares two ways to prevent inflammation and comfort you after cataract surgery: usual antibiotic/steroid eye drops versus a “no-drops” option that is placed during surgery. It mainly looks at patient preference, comfort, and ease of treatment after surgery.
Garden City, New YorkAges 22–100 - NCT04240652Recruiting
Diabetes eye screening and prevention program for eye disease
This program aims to screen people for diabetic eye problems early and help prevent vision loss over time. It may help you if you have type 2 diabetes (or you’ve been invited as a diabetes/non-diabetes participant) and can safely take part in the study activities.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT01195558Recruiting
Registry survey for people who are blind and have sleep problems
This study is a registry survey that collects information about sleep problems and daytime sleepiness. It may help researchers better understand sleep issues in people who are blind and plan future studies or treatments.
Washington D.C., District of ColumbiaAges Any age - NCT04549935RecruitingPhase 4
Testing eye drops and procedures after two-eye surgery
This Phase 4 study looks at a treatment plan around the time of planned surgery on both eyes (called RLE). It may help the researchers learn how safe and effective the approach is for improving eye outcomes after surgery.
Bozeman, MontanaAges 22–75 - NCT04635020Recruiting
iStent versus laser for exfoliation glaucoma with cataract
This trial compares two treatment options for people with exfoliation glaucoma who also have cataracts: a tiny implant placed during cataract surgery (iStent) versus laser treatment. It aims to see which approach better controls eye pressure over 12 months and improves outcomes.
HelsinkiAges 50–100 - NCT04603222Recruiting
Testing a medicated eyelid brush for blepharitis
This trial tests the SUMMIT BRUSH to see if it helps treat blepharitis, an eyelid problem that can be linked to bacteria or tiny mites. It checks whether using the brush improves eyelid signs and symptoms in people who have specific visible findings on exam.
Boulder, ColoradoAges 18 years+ - NCT04665726Recruiting
Natural history study of Usher syndrome hearing and vision changes
This study follows people with Usher syndrome over time to better understand how hearing and vision symptoms change. It may help researchers measure disease progression and support future treatments.
ParisAges Any age - NCT04651530Recruiting
Endoscopic laser treatment for normal-pressure glaucoma
This study tests an endoscopic laser procedure to lower eye pressure and slow damage in people with normal-tension glaucoma. It may help protect the optic nerve, especially if your glaucoma is stable on drops and you also have a cataract.
HelsinkiAges 55–100 - NCT04799002RecruitingPhase 3
Topotecan and melphalan for eye-sparing retinoblastoma treatment
This trial studies whether a combination chemotherapy treatment (topotecan plus melphalan) can help children with retinoblastoma while keeping the eye when possible. It’s a Phase 3 study, meaning it’s testing effectiveness in a larger group of patients.
Guangzhou, GuangdongAges Any age - NCT04833491Recruiting
Eye measurements before cataract surgery and vision quality after
This study uses very specific eye measurements done before cataract surgery to see how they relate to the clarity of vision after surgery. It may help surgeons choose the best surgical approach and improve visual outcomes.
HangzhouAges 2–90
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,762 recruiting ophthalmology studies from the U.S. registry right now, out of 2,739 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.