Comparing standard closure to a reinforcement mesh for high-risk abdominal surgery
Part of Injuries & trauma clinical trials.
This trial tests whether adding a special mesh (TIGR Matrix) to close the belly after surgery helps prevent complications in people at high risk. It may be an option if you are having a repeat abdominal surgery and have certain health conditions.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are having a repeat operation on your belly (abdomen).
- You are over 80 years old, or have a severe health condition like advanced COPD, low albumin, sepsis, or diabetes with complications.
- You have a body mass index (BMI) between 35 and 45, or over 45 without other risk factors.
- You are a smoker (at least 10 cigarettes a day for a year), or you take steroids, chemotherapy, or have had radiation to the belly area.
- Your surgical wound will be at least 10 cm long.
- You do not have an existing mesh from a previous surgery, an incisional hernia, or an infected wound.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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