Immune cells for viral infections after transplant
Part of Infections clinical trials.
This trial tests whether specially grown immune cells (T cells) can fight common viruses like CMV, EBV, or BK virus in people with weakened immune systems, such as after a stem cell or organ transplant. It may help when standard medicines don't work or can't be used.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a current infection with CMV, EBV, ADV, BKV virus that isn't responding to medicine or can't be treated with standard drugs.
- Your virus levels are high or you have symptoms like fever, diarrhea, or swollen glands.
- Your blood cell counts have started to recover after a transplant (neutrophils ≥ 500, platelets ≥ 20,000).
- Your kidney and liver function are fairly good (creatinine, bilirubin, and liver enzymes within 2-3 times the upper normal limit).
- If the immune cells come from a donor, that donor must be healthy and free of HIV, hepatitis B/C, and tuberculosis.
- You haven't had other experimental cell therapies in the last 30 days, and you are not pregnant.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether specially trained immune cells (virus-specific T cells) can safely treat stubborn viral infections after a stem cell transplant. It focuses on children and young adults who have not responded to standard antiviral treatments.
This trial studies whether directly infusing donor-made immune cells (virus-fighting T-cells) is safe and feasible in people who still have viral infections after a stem cell transplant. It may help your body control infections from adenovirus, CMV, or EBV when standard antiviral treatments aren’t working.
This trial tests a special T-cell treatment (LB-DTK-MV) for people with virus infections (CMV, BKV, EBV) that did not get better with standard medicines. It is for patients who had a stem cell transplant or certain cancer therapies like CAR-T or bispecific antibodies.
This Phase 3 trial tests giving special immune cells from your stem-cell donor to treat difficult-to-control viral infections after a stem cell transplant. It may help your body fight the virus when standard antiviral medicines haven’t worked well enough.
This trial tests a treatment using specially trained immune cells (virus-specific T-cells) to fight stubborn infections with adenovirus, CMV, or EBV in people with weakened immune systems, such as after a stem cell or organ transplant.
This trial tests a treatment using specially grown T-cells (a type of immune cell) to fight certain viruses that won't go away with standard medicines. It is for people who have had a stem cell or organ transplant, or who have a weak immune system, and who are struggling with adenovirus, CMV, or EBV infections.
Hear when a new EBV Infection trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.