Belimumab plus rituximab for early diffuse scleroderma skin disease
Part of Skin clinical trials.
This Phase 2 study tests whether combining belimumab and rituximab can improve skin thickening in people with early diffuse cutaneous systemic sclerosis (dcSSc). It may help slow the disease process and improve skin symptoms, but it also requires screening for immune and infection risks.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’re age 18 to 80.
- You have diffuse cutaneous systemic sclerosis (dcSSc), diagnosed by specific medical criteria.
- Your disease started less than or equal to 3 years ago (based on the first symptom that wasn’t Raynaud’s).
- Your skin thickening score is above 14 on the modified Rodnan Skin Score (mRSS).
- You must be able to give informed consent and speak English for study communication.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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