Clin2
NCT03878121Possibly a fitRecruiting

Ad4-HIV vaccine study for healthy adults and partners

Healthy Volunteer

Part of Infections clinical trials.

This Phase 1 study tests whether an experimental HIV vaccine (made from a harmless viral vector) is safe and helps the body build immune defenses. It includes healthy volunteers and, in some groups, their close partners, with careful screening and follow-up visits.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
300 people
Ages
18 years to 65 years
Study type
Interventional

Who can take part

  • You are between 18 and 49 years old (if you’re the vaccine recipient), or 18 to 65 (if you’re a household or intimate contact).
  • You have a negative HIV test before joining and agree to share results with the study team.
  • You can attend all scheduled follow-up visits and complete required study tests for the full study time.
  • You agree to have blood/samples stored for possible future research.
  • If you can become pregnant, you must have a negative pregnancy test and follow the study’s pregnancy prevention rules during the study period.
  • You must have no immune system problems (like immunodeficiency/autoimmune disease) and not take immune-suppressing medicines.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06796686Recruiting· Phase 1
HIV vaccine safety and immune response study for healthy adults

This trial tests a new two-part HIV vaccine regimen in healthy adults without HIV. The goal is to see if it is safe and produces an immune response that could help prevent HIV.

San Francisco, California
NCT06617091Recruiting· Phase 1
HIV vaccine trial for healthy adults with and without HIV

This trial tests an experimental HIV vaccine in healthy adults, including those living with HIV. The goal is to see if the vaccine is safe and prompts an immune response.

Mtubatuba, KwaZulu-Natal
NCT07675629Not yet recruiting· Phase 2
HIV vaccine safety study for healthy adults

This trial tests an experimental HIV vaccine to see if it is safe and triggers an immune response. It is for healthy adults who are HIV-negative and at low risk for HIV.

Boston, Massachusetts
NCT06205056Recruiting· Phase 1
HIV vaccine safety and immune response test

This trial tests a new combination HIV vaccine in healthy adults to see if it is safe and produces an immune response. If you are at low risk for HIV, you may help researchers learn more about future prevention strategies.

Kampala
NCT07757802Recruiting· Phase 1
HIV vaccine nanoparticle and mRNA booster for healthy adults

This study tests a new HIV vaccine that uses tiny particles (nanoparticles) and an mRNA booster — similar to some COVID vaccines. The goal is to see if it is safe and helps your body fight HIV. It's for healthy adults who do not have HIV.

San Francisco, California
NCT07390474Recruiting· Phase 1
HIV vaccine safety and immune response study for healthy adults

This study tests two experimental mRNA-based HIV vaccines to see if they are safe and create an immune response. It is for healthy adults aged 18 to 55 who do not have HIV.

Atlanta, Georgia

Hear when a new Healthy Volunteer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.