Two ointments for painful recent anal fissures
Treatments studied
Part of Digestive system clinical trials.
This Phase 2 trial compares MEBO ointment with diltiazem ointment to see which one heals an acute anal fissure (a small tear causing pain). You may be able to join if your fissure is recent and very painful, and you can pause other anal-area ointments during the study.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be 18 years or older
- Your painful anal fissure must have started within the last 90 days
- You must have at least twice a week pain with bowel movements and average pain of at least 3/10
- On the exam, a doctor must see a specific type of fissure (radial) with firm, thickened edges
- Be willing to stop other anal-area creams/ointments for at least 2 weeks before starting the study and during the trial
- Be willing to be examined and able to sign consent
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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