Study of tradipitant for severe or critical COVID-19
Treatments studied
Part of Infections clinical trials.
This trial tests whether tradipitant can improve outcomes for adults with severe or critical COVID-19, including pneumonia and low oxygen. It may help patients whose lungs are significantly affected and who need careful hospital-level care.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are age 18 to 90
- You have a confirmed COVID-19 infection test (RT-PCR)
- Your hospital says your COVID-19 is severe or critical
- You have pneumonia seen on a chest X-ray or CT scan
- You have low oxygen (oxygen saturation under 92%) or fever as defined by the study
- You are not pregnant and can give consent (or a legal representative can)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests an oral drug called SPI-1005 for people hospitalized with moderate COVID-19. The drug may help reduce inflammation and protect the lungs, and the study will compare it to a placebo (a pill with no active medicine) to see if it helps people recover.
This study is testing the safety of an investigational drug called tradipitant in people with stomach paralysis (gastroparesis) caused by unknown reasons or diabetes. It looks at how well the drug is tolerated over time.
This is a special single-patient program for a person with gastroparesis who has moderate to severe nausea. It provides access to an investigational drug called tradipitant, which may help relieve nausea, when no other clinical trials are available.
This trial studies whether PF-07321332 (with ritonavir) helps children under 18 who have COVID-19 at home but are at high risk of severe illness. It looks at whether starting treatment early can reduce progression to worse disease.
This trial tests a new drug, ratutrelvir, for people with mild to moderate COVID-19. It aims to find a safe and effective dose to help you feel better faster.
This study tests a new antibody medicine for people with COVID-19 who are at high risk of getting very sick. If you qualify, you would receive the study drug or a placebo (inactive substance) to see if it helps you recover without needing to go to the hospital.
Hear when a new Coronavirus Infection trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.