Clin2
NCT04443478Possibly a fitRecruiting

Keyhole versus open lymph node surgery for junction cancer

Gastric Cancer

Part of Cancer, Digestive system clinical trials.

This trial compares two ways of removing lymph nodes during surgery: keyhole (laparoscopic) versus open surgery. It is for people with esophagus-stomach junction adenocarcinoma, aiming to see which approach works better and is safer.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
1,036 people
Ages
18 years to 80 years
Study type
Observational

Who can take part

  • You are age 18 to 80
  • You are well enough for surgery (Karnofsky 70%+ or ECOG 0–2)
  • Your biopsy confirms adenocarcinoma at the esophagus-stomach junction
  • Your tumor invasion into the esophagus is 2 cm or less
  • Your scans show stage CT2-4a, lymph nodes N0–3, and no distant spread (M0)
  • Your blood tests and organ function are strong enough for surgery (including blood counts, liver, bilirubin, kidney, and albumin)

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05537129Recruiting
Laparoscopic vs open stomach surgery for stomach cancer

This trial compares two ways surgeons remove the entire stomach (total gastrectomy): laparoscopic (small keyhole cuts) versus open surgery (one larger cut). It’s testing which approach is safer and works better for people with certain stages of stomach cancer.

Shanghai, Shanghai Municipality
NCT06300879Recruiting
New surgery technique for upper stomach or junction cancer

This study tests a new surgical technique for removing cancer in the upper stomach or where the stomach meets the esophagus. It aims to see if this technique is safe and effective for people with early-stage adenocarcinoma who haven't had other cancer treatments.

Shanghai, Shanghai Municipality
NCT06202105Recruiting
Laparoscopic vs open total gastrectomy for advanced stomach cancer

This trial compares two types of surgery for stomach cancer that has grown into deeper layers but has not spread to distant organs. The goal is to see if a keyhole (laparoscopic) approach is as safe and effective as traditional open surgery.

Bien Hoa, Dong Nai
NCT03385018Recruiting
Laparoscopic total stomach surgery trial for stomach cancer

This trial studies whether a minimally invasive (laparoscopic) removal of the entire stomach, along with lymph node removal, can be done safely and effectively for certain stomach cancers. It may be an option if your cancer is in the stomach, has limited spread to nearby lymph nodes, and can be fully removed.

Seoul
NCT05450835Recruiting
Surgery technique comparison for stomach cancer near the esophagus

This study compares two ways surgeons reconnect the digestive tract after removing the whole stomach for certain stomach cancers near the esophagus. It aims to see which technique is safer and leads to better recovery and outcomes.

Quanzhou, Fujian
NCT07142122Recruiting
Comparing two types of stomach surgery for early upper gastric cancer

This trial compares two laparoscopic surgeries for early-stage stomach cancer in the upper part of the stomach. It looks at whether preserving a nerve (celiac branch of vagus nerve) during surgery leads to better recovery while still removing the cancer safely.

Fuzhou, Fujian

Hear when a new Gastric Cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.