Testing genetic risk for acetaminophen-related liver injury
Part of Digestive system clinical trials.
This study looks at whether certain genes can predict who is more likely to get liver injury after taking acetaminophen (also found in some cold/flu medicines). By comparing people who were affected with people who were not, it may help doctors identify higher-risk patients in the future.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You (or your child) took acetaminophen or a medicine that contains acetaminophen
- You can provide blood and/or urine tests for acetaminophen if the exact dose/timing is unclear
- Your liver blood tests (ALT or AST) rose to at least 1000 IU/L after acetaminophen use
- Your RUCAM score (a liver-injury likelihood scoring system) is above 6
- You are age 14 or older, and you (or your guardian) can sign consent
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study compares two methods (RUCAM and RECAM) to better identify what caused a recent liver injury. It may help doctors find the right cause and treatment faster.
This trial builds a prediction model to identify drug-related liver injury (DILI) by looking at your blood test patterns, timing, and expert diagnosis. It may help improve how doctors recognize this condition earlier and more accurately.
This study follows people who developed liver injury from a medicine (not from other causes). It aims to better describe different types and severities of drug-related liver injury and may help improve how clinicians recognize and manage it.
This study puts people with a past drug- or herbal-related liver injury into a research registry. The goal is to better understand why the injury happens so doctors can prevent and recognize it sooner.
This study looks at how your genes affect the way your body handles medications. It aims to improve treatment by understanding genetic differences, especially if you take multiple medications.
This study looks at your genes to see how they might affect how your body processes many medications. You may be a good fit if you take five or more different medicines and want to help researchers learn more about personalized medicine.
Hear when a new Acetaminophen trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.