Check ER004 given in the womb for a genetic tooth-skin disorder
Part of Genetic & congenital, Skin clinical trials.
This Phase 2 study tests ER004 put into the amniotic fluid during pregnancy to treat male babies with X-linked hypohidrotic ectodermal dysplasia (XLHED). It also looks at effects in affected male relatives with the same gene change.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Pregnancy must be confirmed, and you must be no later than 23 weeks 6 days pregnant
- The mother must be a confirmed carrier of an EDA gene mutation (genetic test confirms this)
- The baby must be diagnosed with XLHED and be male
- There must be no major extra body problem besides XLHED that could strongly affect safety or outcomes
- The family must include an untreated male relative (6 months to 75 years) with the same EDA mutation
- There must be no active serious pregnancy infection and no known maternal HIV infection
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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