Prevent Crohn’s return after surgery: endoscopy-guided vs standard medicine
Part of Digestive system clinical trials.
This study compares two ways to choose biologic (targeted) medicines after Crohn’s surgery to help stop Crohn’s from coming back in the bowel. It may help you avoid or delay repeat inflammation by adjusting treatment based on endoscopy findings.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have Crohn’s disease confirmed by tests (scan, scope, and/or biopsy).
- You are age 18 to 80, and you (or your legal representative) can give consent.
- You had an ileocolonic resection with the bowel reconnected within about 3–40 days of starting the study (with extra timing rules if you had a temporary ileostomy).
- Your Crohn’s puts you at higher risk of coming back after surgery (examples include penetrating disease, multiple past resections, current smoking, or biologics within 3 months).
- Your surgeon removed all inflamed colon, and your case is considered “curative” after surgery.
- You must be able and willing to start biologic therapy at the study’s randomization time.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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