Monoclonal antibodies for BK virus infection

This study tests a new medicine (AIC468) to see if it can help clear BK virus from the blood of people who have recently had a kidney transplant. Participants will receive either the study drug or a placebo (a dummy pill) to compare outcomes.

This study is creating a registry to learn how the immune system responds to BK virus in people who have recently received a kidney transplant from a deceased donor. Researchers hope this information will help improve treatment for BK virus infections.

This study looks at the type and genetic makeup of BK virus in kidney transplant patients and their donors. It aims to find patients at higher risk for a kidney infection caused by the virus, which could help improve monitoring and treatment.

This trial tests a treatment using special immune cells (called cytotoxic T lymphocytes) to fight BK or JC virus infections in people with weakened immune systems, such as cancer patients or organ transplant recipients. It may help control the virus and reduce related complications.

This study looks at how BK virus affects the body and how your immune system responds after a lung transplant. It may help doctors better understand and manage virus-related complications in transplant recipients.

This Phase 1/2 study tests lab-made immune cells that specifically target BK virus in people whose BK infection keeps coming back or doesn’t improve. It may help by boosting the body’s ability to clear the virus, especially when standard antiviral treatments don’t work or can’t be tolerated.