Clin2
NCT05549297Possibly a fitRecruiting

Tebentafusp plus choice of treatment for advanced melanoma

Advanced Melanoma

Treatments studied

Part of Cancer, Skin clinical trials.

This Phase 3 study compares tebentafusp treatment against the doctor’s choice of standard options in people with previously treated advanced melanoma. It aims to see which approach works better for controlling the cancer and improving outcomes.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
540 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • Your melanoma must test positive for HLA-A*02:01 (a specific immune-marker).
  • You have non-eye melanoma that is stage III or stage IV and cannot be fully removed with surgery.
  • You can provide tumor tissue from a past biopsy or agree to a new biopsy that was not done after radiation to that area.
  • Your study doctor must describe your melanoma as measurable or not-measurable by standard imaging rules, and your health status must be good (ECOG 0–1).
  • You must be willing to use highly effective birth control if applicable and agree to give required blood/tumor samples for lab testing.
  • You must be able to sign informed consent and follow study rules.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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