Testing a plan to preserve the anus after rectal chemo-radiation
Part of Cancer, Digestive system clinical trials.
This Phase 2 study tests a “total neoadjuvant” (chemo plus radiation before the main treatment) plan to see if some people with low rectal cancer can keep their anus. It may help you avoid permanent colostomy if your cancer responds well and you meet the study rules.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are age 18 or older
- Your rectal cancer is confirmed by biopsy, and the tumor is within 5 cm of the anus
- Your scans suggest early spread: cT1-3, no lymph nodes in the pelvis (N0), and no distant spread (M0)
- You have never had cancer treatment for this rectal cancer before (no chemo, radiation, or local surgery)
- You must be able and willing to understand the study and sign informed consent
- Your blood counts and liver/kidney function must be within study safety limits
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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