Clin2
NCT05575804Possibly a fitRecruiting

GQ1001 plus pyrotinib for HER2-positive metastatic breast cancer

Advanced/ Metastatic Her-2 Positive Breast Cancer

Part of Cancer, Women’s health & pregnancy clinical trials.

This trial tests a combination of two targeted drugs, GQ1001 and pyrotinib, for people with HER2-positive breast cancer that has spread to other parts of the body and has not responded to at least one prior treatment. The goal is to see if this combination can shrink tumors or slow cancer growth.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
32 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You are between 18 and 75 years old.
  • Your breast cancer is HER2-positive (a protein that helps cancer grow) and has spread to other parts of the body.
  • You have already tried at least one standard treatment for advanced cancer, and it did not work or stopped working.
  • You have measurable tumors that can be seen on scans.
  • Your heart, liver, kidneys, and blood counts are within certain safe limits.
  • You have not had certain previous treatments, like a specific type of antibody-drug conjugate (a targeted chemotherapy) or the combination of pyrotinib and capecitabine.
  • You do not have untreated or worsening brain tumors that cause symptoms.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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