Dihydromyricetin for early alcohol-related liver injury
Part of Mental health clinical trials.
This early-stage study tests a supplement-like drug called dihydromyricetin to see what dose is safe and whether it can help prevent or improve alcohol-associated liver disease. It is meant for adults who have not yet developed significant liver damage and do not have alcohol use disorder.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be 18 to 60 years old
- No history of alcohol use disorder or alcohol-associated liver disease
- Weigh at least 50 kg
- Do not have advanced liver disease or other acute (sudden) liver problems
- Not pregnant and willing to avoid pregnancy during the study
- Have no HIV infection, pancreatic/biliary disease, or other conditions that could block absorption of the study drug
- Not taking certain medicines that strongly affect a liver enzyme called CYP3A4
- Your liver blood test risk score (FIB-4) must be 1.30 or less (not above 1.30)
- On the AUDIT questionnaire, your score must be 8 or less (no alcohol use disorder by this test)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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