Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,769 recruiting studies in this area right now.
By phase
- Not applicable6,417
- Phase 2493
- Phase 1249
- Phase 3236
- Phase 4212
- Phase 1/Phase 294
- Phase 2/Phase 368
Top conditions
- Anxiety386
- Depression382
- Alzheimer Disease337
- Autism Spectrum Disorder240
- Dementia224
- Mild Cognitive Impairment193
- Schizophrenia185
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder142
- Opioid Use Disorder141
- Stress117
- PTSD106
- Mental Health99
- Autism95
- Mild Cognitive Impairment (MCI)88
- Suicidal Ideation87
Leading sponsors
- VA Office of Research and Development105
- Yale University87
- Massachusetts General Hospital76
- Stanford University69
- Assistance Publique - Hôpitaux de Paris63
- Johns Hopkins University61
- University of California, Los Angeles58
- The University of Hong Kong52
- University of Pennsylvania52
- Karolinska Institutet49
Where studies are running
- California517
- Massachusetts263
- New York255
- Texas209
- Maryland174
- Pennsylvania169
- Florida145
- Alabama118
- Arizona110
- Illinois104
Recruiting studies7,769 total
- NCT05732155RecruitingPhase 2
MDMA-assisted therapy for war-related PTSD
This study tests whether combining MDMA with talk therapy can help people with post-traumatic stress disorder (PTSD) from war experiences. It involves both individual and group therapy sessions, and the medication is given during some sessions.
AfulaAges 18 years+ - NCT05780450Recruiting
Brain stimulation for long covid headaches and pain
This trial tests a safe, non-invasive brain stimulation technique (transcranial direct current stimulation, or tDCS) to see if it can reduce persistent headaches and chronic pain in people with long covid. If you have ongoing pain after a confirmed covid infection, this could offer a new way to find relief.
Paiporta, ValenciaAges 16 years+ - NCT07874594Recruiting
Brain training to improve sleep after a first stroke
This study tests a treatment that may help reduce brain inflammation and improve sleep in people who have had a first stroke and now have trouble sleeping. It uses a non-invasive technique called remote ischemic conditioning, which involves brief, repeated cycles of a blood pressure cuff on the arm.
Chengdu, SichuanAges 18–80 - NCT07876908Recruiting
Magnetic brain therapy for older adults with hard-to-treat depression
This trial tests a new intensive magnetic brain treatment (SAINT) for older adults whose depression has not improved with standard treatments. It aims to see if this treatment can also help with memory concerns, which are common in this group.
Costa Mesa, CaliforniaAges 65 years+ - NCT07455526Recruiting
Help to quit smoking for veterans with mental illness
This program helps veterans who have a serious mental illness and use tobacco to get more support for quitting, such as connecting them with treatment options during their mental health visits.
Baltimore, MarylandAges Any age - NCT07876570Recruiting
Predicting memory decline with brain and blood tests
This study follows older adults with normal memory, mild memory problems, or dementia over a year to see if brain scans and blood tests can predict who will get worse. It may help find early warning signs of Alzheimer's and other dementias.
Beijing, Beijing MunicipalityAges 50 years+ - NCT07708246Recruiting
Parent-led social skills training for children with autism
This study teaches parents to run play-based activities at home that help children with autism improve social skills. Parents attend one training session and get monthly video check-ins, and the program runs for 6 months.
Shanghai, Shanghai MunicipalityAges 3–10 - NCT07875166Recruiting
Skills training group for borderline personality disorder
This trial tests a group therapy program called Dialectical Behavior Therapy (DBT) skills training, which teaches practical skills to manage emotions and improve relationships. Participating may help you feel more in control of your emotions and daily life.
Padre Las Casas, AraucaniaAges 18 years+ - NCT07876245Recruiting
Gentle massage for toddlers with autism
This study tests whether a simple, gentle massage routine can help toddlers with autism. It looks at how the massage might affect brain activity and parent-child interaction.
Shanghai, Shanghai MunicipalityAges 1.5 years–2 years - NCT07521319Recruiting
Wearable device guide for sleep apnea and insomnia
This study tests a wearable device that helps guide treatment for people who have both sleep apnea and insomnia. It may help improve your sleep quality and daytime symptoms.
Tainan, TaiwanAges 20–80 - NCT03745339Recruiting
Smell-based memory task in people with opioid-use disorder
This study tests how people learn and infer what something means using a smell-and-memory task. It compares people with opioid-use disorder who are abstinent, those in maintenance treatment, and healthy controls to see what affects learning and decision-making after opioid use.
Baltimore, MarylandAges 21–60 - NCT07637669Recruiting
Smell and decision-making in people with HIV and substance use
This study looks at how smell and decision-making are affected in people living with HIV and/or substance use disorders. You may join one of four groups based on your HIV status and substance use history, and you will complete smell tests and computer tasks, with an optional MRI.
Baltimore, MarylandAges 18–65 - NCT07169630RecruitingPhase 1
PET scan study for Alzheimer's or mild cognitive impairment
This study uses a special PET scan to look at a brain protein called PDE4 in people with Alzheimer's disease or mild cognitive impairment. It may help researchers understand how this protein is involved in memory and thinking problems.
Bethesda, MarylandAges 50–100 - NCT06832761Recruiting
Lifestyle help for people with early memory concerns
This trial tests whether a lifestyle program can help people with mild memory problems (subjective cognitive decline or mild cognitive impairment) who also have at least two things that increase their risk for dementia, like high blood pressure or lack of exercise. If you're 50 or older and have these memory issues and risk factors, you may be able to join.
AmsterdamAges 50 years+ - NCT04166071Enrolling by invitationEarly Phase 1
Testing whether opioids plus support change learning behavior
This early study tests how opioid medicine, along with social support, affects how people learn or “unlearn” certain responses. If you’re healthy and meet safety requirements, it may help researchers understand how support could change the effects of pain-related medicines on behavior.
Los Angeles, CaliforniaAges 18–35 - NCT06676059Recruiting
Substance use monitoring study with a smartphone app
This study uses a smartphone app and daily surveys to track alcohol or drug use. It aims to create a database for future research on addiction patterns and recovery.
Baltimore, MarylandAges 18–120 - NCT03019757Recruiting
Testing ways to tell dementia causes apart
This study looks at how to distinguish Alzheimer’s disease, Lewy body dementia, and Parkinson’s disease when someone has memory and thinking problems. It may help doctors choose the most accurate diagnosis and treatment path for the right condition.
Columbus, OhioAges 18 years+ - NCT06366724RecruitingPhase 2
Life Improvement Trial for ME/CFS
This trial tests a new treatment for ME/CFS (chronic fatigue syndrome) that includes symptoms like dizziness when standing. It uses a smartphone app to track your progress and aims to see if the treatment can improve your daily life.
Boston, MassachusettsAges 18–70 - NCT07472127Recruiting
Emotional preparedness training for new nurses
This study tests a program to help new nurse residents feel more emotionally prepared for their jobs. It may improve confidence and readiness in the workplace.
Orlando, FloridaAges Any age - NCT07640802Recruiting
Comparing talk therapies for irritability in children
This study compares two types of talk therapy for children who have frequent, intense irritability or temper outbursts. The goal is to see if a specific new therapy works better than a supportive, educational approach that does not include the active treatment techniques.
Bethesda, MarylandAges 8–17 - NCT07463001Recruiting
Teamwork program to improve school attendance for kids
This trial tests a teamwork-based program to help kids who have trouble attending school catch up with their attendance. It brings together parents, school, and specialists to support your child, and aims to find ways to help kids get back to class regularly.
BergenAges 9–15 - NCT07764536Recruiting
Parent training plus a digital tool for child temper outbursts
This trial tests whether a digital tool can make parent training more effective for children who have frequent temper outbursts and irritability. The training helps parents learn skills to manage their child's behavior, and the digital tool may help them practice and apply those skills.
Bethesda, MarylandAges 8–13 - NCT06284889Recruiting
Behavioral activation for depression in older adults
This study tests a program called Behavioral Activation, a type of talk therapy that helps you engage in positive activities to improve mood. If you are 65 or older and have mild to moderate depression, you may be able to join this telephone-based treatment.
Uppsala, UpplandAges 65 years+ - NCT05830266Recruiting
Mindfulness program to help mother–baby bonding in pregnancy and after
This study tests a mindfulness-based program to improve mother–baby bonding by supporting mood, anxiety, and stress during and after pregnancy. It may help if you’re currently having higher-than-average depression, anxiety, or stress symptoms.
Tilburg, North BrabantAges 18 years+
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,769 recruiting psychiatry studies from the U.S. registry right now, out of 12,243 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.