Biopsy or surgical removal for glioblastoma in older adults
Part of Cancer clinical trials.
This study compares doing a tissue biopsy versus fully removing the tumor in people age 70 and older with glioblastoma. It looks at which approach is safer and helps people get through treatment and follow-up better.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 70 years old or older
- Your MRI shows a glioblastoma pattern with a ring-like enhancing tumor and signs of tumor death in the center
- Your overall ability to function is fair-to-good (Karnofsky score of 70 or higher)
- You can sign written informed consent
- Your tumor is not in the cerebellum, brain stem, or the brain’s midline
- You do not have multiple tumor spots (only one area on contrast MRI)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial uses advanced imaging to help surgeons remove as much of a malignant brain tumor as safely possible. It may be a good fit if you have a new diagnosis of glioblastoma or a certain astrocytoma and are healthy enough for surgery.
This study compares whether having surgery to remove as much of the tumor as possible (resection) or just taking a small sample (biopsy) leads to better outcomes for people with a fast-growing brain tumor (high-grade glioma). The goal is to help guide treatment decisions.
This study compares receiving palliative care (supportive treatments) versus surgery (removing the tumor) for people with a high-grade glioma, a fast-growing brain tumor. The goal is to find out which approach improves quality of life and survival.
This trial is testing a new way to find and remove glioblastoma brain tumors using a special MRI scan. It may help doctors remove more of the tumor safely during surgery.
This study aims to improve understanding of glioblastoma (and gliosarcoma) by preserving live, usable brain-tissue samples during brain surgery. If you’re having repeat tumor surgery or your scans suggest these cancers, the study may ask to collect tissue for research.
This trial tests if removing only part of the affected brain lobe (instead of the whole lobe) is safe and effective for a specific type of glioblastoma that has certain gene changes (IDH wild-type and TERT promoter mutation). It is for people whose tumor is in one lobe of the brain and can be completely removed based on MRI.
Hear when a new Glioblastoma trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.