TUMT vs PAE to ease severe urinary symptoms from an enlarged prostate
Part of Kidney & urinary clinical trials.
This trial compares two catheter-based treatments—TUMT and PAE—to see which better reduces severe urinary symptoms caused by an enlarged prostate (BPH). It may help you choose a treatment option if medicines are not suitable or you still have significant symptoms.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You can understand the study and sign consent.
- You have severe urinary symptoms from an enlarged prostate (BPH), with an IPSS score of 20 or higher.
- Tests show blockage and a large prostate: weak urine flow (Qmax 15 mL/second or less) and prostate size of at least 50 mL.
- You are not able to take prostate medicines (they didn’t work or aren’t safe for you, or you prefer not to take them).
- You must not have certain conditions such as bladder cancer being treated now, recent pelvic radiation, active urinary infection, urethral narrowing/strictures, bladder stones left in place, nerve-related bladder problems, or high bleeding risk.
- You must be able to safely undergo the procedure, including no iodine contrast allergy and kidney function with eGFR 35 mL/min or higher. High bleeding risk (INR > 1.6) and inability to have light sleep sedation can also exclude you.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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