Clin2
NCT05709249Possibly a fitRecruiting

Chinese herbal medicine to help prevent colon cancer return

Colon Cancer

Part of Cancer, Digestive system clinical trials.

This Phase 3 study tests whether a Chinese herbal “decoction” (called XLJDOD) given after surgery and chemo can lower the chance that colon cancer comes back. It may help people with higher-risk colon cancer (Stage IIIB or IIIC) stay cancer-free longer.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
730 people
Ages
20 years to 80 years
Study type
Interventional

Who can take part

  • Your colon cancer was confirmed by pathology (biopsy/surgery tests).
  • You had surgery to remove the tumor completely with clear margins (R0), and you finished at least 3 months of chemo with 5-fluorouracil (5-FU) or related plans.
  • You are within 3 months after finishing your adjuvant (after-surgery) chemotherapy.
  • Your colon cancer stage is IIIB or IIIC, and scans show no signs of recurrence right now.
  • You’re age 20 to 80, and your daily functioning is rated 0 to 2 (able to do most activities).
  • You can sign consent and do study follow-ups.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06609551Recruiting· Phase 3
ctDNA-guided chemo choice for elderly colon cancer patients

This trial tests whether using a ctDNA blood test can help choose the best chemotherapy after colon cancer surgery for people aged 70–80. It aims to make treatment more personalized and reduce side effects.

Hangzhou, Zhejiang
NCT05534087Recruiting· Phase 3
Blood test guided chemo after colon cancer surgery

This study tests whether giving additional (adjuvant) chemotherapy based on a special blood test—circulating tumor DNA (ctDNA)—can lower the risk of colon cancer coming back. It targets people with stage II–III colon cancer whose blood test is positive for minimal residual disease (MRD) after completing standard chemo.

Busan
NCT06242418Recruiting· Phase 2
ctDNA-Guided Chemo for Stage III Colon Cancer

This trial tests whether checking for cancer DNA in your blood (ctDNA) can help doctors decide if you need extra chemotherapy after surgery for stage III colon cancer. It aims to personalize treatment and avoid unnecessary chemo.

Guiyang, Guizhou
NCT06596343Not yet recruiting· Phase 2
Traditional Chinese medicine after colon cancer surgery

This study tests whether adding traditional Chinese medicine to standard chemotherapy after colon cancer surgery helps patients recover and live longer. If you are between 18 and 75 and have stage III colorectal cancer, this could be an option to discuss with your doctor.

Hangzhou, China
NCT07854405Not yet recruiting
Chinese herbal granules with standard care for advanced colorectal cancer

This study tests whether adding a traditional Chinese medicine called Zhen-Qi-Jie-Du granules to usual palliative care can improve outcomes for people with advanced colorectal cancer. It aims to see if the combination offers extra benefits without causing more harm.

Nanjing, Jiangsu
NCT07129499Not yet recruiting
Herbal granules to prevent high-risk colon polyps from turning into cancer

This trial tests a Chinese herbal medicine called Shenbai Granules to see if it can prevent high-risk colon polyps from turning into cancer. If you have had such a polyp removed and fit the traditional Chinese medicine pattern, you may be able to join.

Nanjing, Jiangsu

Hear when a new Colon Cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.