Test stool transplant to treat irritable bowel syndrome
Treatments studied
Part of Digestive system clinical trials.
This trial studies fecal microbiota transplantation, which is transferring stool bacteria from a healthy donor to help rebalance gut microbes. If you have irritable bowel syndrome (IBS) that hasn’t improved after several standard treatments, this study may see whether it reduces your symptoms and is safe.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have IBS diagnosed using Rome IV criteria (a symptom-based checklist).
- You are between 18 and 70 years old.
- You have tried at least 3 usual IBS treatments and they did not work.
- You do not have warning signs like unexplained weight loss or blood in the stool.
- You are not pregnant, planning pregnancy, or breastfeeding.
- You haven’t used probiotics in the last 3 months and haven’t used antibiotics in the last month.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether transferring stool bacteria from a healthy donor (fecal microbiota transplantation) can improve symptoms of irritable bowel syndrome (IBS). It may help by changing the gut bacteria that can influence digestion and gut discomfort.
This trial tests whether transferring stool bacteria to the gut (fecal microbiota transplantation) can reduce symptoms of irritable bowel syndrome with constipation. It may help by changing the gut microbiome, but you must meet safety and health requirements.
This trial tests whether a fecal microbiota transplantation (FMT), which transfers healthy bacteria from a donor into your gut, can reduce severe irritable bowel syndrome (IBS) symptoms. FMT is being studied as a possible new treatment for people with IBS that hasn't improved with other treatments.
This study tests whether fecal microbiota transplantation (a stool-based treatment to change gut bacteria) can reduce symptoms of irritable bowel syndrome (IBS) that comes with diarrhea. You may be eligible if you’re an adult with diarrhea-predominant IBS and recent colonoscopy results that rule out other intestinal diseases.
This trial tests whether putting stool (fecal microbiota) from a donor into your bowel can improve symptoms in people with IBS who are not IBS-C. It may help by changing the gut bacteria that can influence IBS symptoms.
This study tests whether taking antibiotics before a fecal microbiota transplant (WMT) improves IBS symptoms. It compares how well the transplant works when patients have antibiotics beforehand versus not.
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