Salvage surgery after chemo-radiation for cervical cancer
Part of Cancer, Women’s health & pregnancy clinical trials.
This trial studies whether doing surgery after standard chemo-radiation can help control cervical cancer that may still be present. It may be an option if your biopsy or PET-CT scan suggests residual tumor in the cervix and/or nearby pelvic lymph nodes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have cervical cancer that is stage Ib3, IIA2, or IIA–IVA (as defined by FIGO 2018), and it’s one of these types: squamous, adenosquamous, or adenocarcinoma
- You already finished the full standard treatment: pelvic external beam radiation plus chemotherapy during radiation, and brachytherapy
- About 4–12 weeks after treatment, tests suggest leftover cancer: either biopsy shows residual cancer, or PET-CT shows active spots in the cervix and/or pelvic lymph nodes (SUVmax ≥ 2.5)
- Your general health score (ECOG) is 0 or 1, meaning you can do most usual activities
- You have no clear reason you can’t have surgery, and your kidneys, liver, lungs, and heart are well enough for the operation
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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