Clin2
NCT05784350Possibly a fitNot yet recruiting

Ultrasound-guided fluid and ondansetron before general anesthesia

Intra-operative Hypotension

Part of Heart & circulation clinical trials.

This trial tests whether using a bedside ultrasound to guide IV fluids, along with a nausea medicine called ondansetron, can prevent blood pressure from dropping after starting general anesthesia. It may help people stay more stable during elective surgeries.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
150 people
Ages
19 years to 99 years
Study type
Interventional

Who can take part

  • Be older than 18 years
  • Plan to have elective surgery (not heart surgery and not during pregnancy) using general anesthesia
  • Your overall health should be mild to moderate (ASA I–III) as judged by the anesthesia team
  • Before anesthesia starts, your blood pressure is not too low (mean arterial pressure not below 60 mmHg)
  • You should not take ACE inhibitors or ARBs on the day of surgery
  • You should not have severe heart failure (ejection fraction under 40%) or serious kidney or liver failure

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06727201Not yet recruiting· Phase 2/Phase 3
Ondansetron for preventing low blood pressure during C-section

This trial tests whether a medicine called ondansetron (commonly used for nausea) can help prevent low blood pressure during spinal anesthesia for planned C-sections. If you are a healthy pregnant woman with a single baby at full term and scheduled for a C-section, you may be able to join.

Asyut
NCT06850740Enrolling by invitation
Spinal ondansetron for hernia repair pain relief

This trial tests if adding ondansetron to standard spinal anesthesia during hernia surgery can provide better pain relief. It may help you need less pain medicine after the procedure.

Ismailia
NCT07336680Not yet recruiting· Phase 4
Testing ondansetron for comfort during emergency stomach bleeding exam

This trial tests whether a nausea medicine called ondansetron helps people feel better and lets doctors work more efficiently during a camera test (endoscopy) for upper GI bleeding. If you need an emergency endoscopy for bleeding, ondansetron may reduce discomfort.

NCT06930456Enrolling by invitation
Comparing two drugs to prevent low blood pressure during spinal anesthesia

This study tests if giving hydrocortisone (a type of steroid) or ondansetron (an anti-nausea drug) before spinal anesthesia can better prevent low blood pressure during surgery for your belly or lower leg.

Port Said, Port Said Governorate
NCT06297499Recruiting· Phase 1
Testing ondansetron to prevent itching after C-section

This trial tests if giving ondansetron before spinal anesthesia can prevent itching that often happens after a C-section. It may help you feel more comfortable during recovery.

Detroit, Michigan
NCT05844501Recruiting· Phase 4
Ondansetron before heart ablation for atrial fibrillation

This trial tests whether ondansetron can help people with atrial fibrillation (an abnormal heart rhythm) around the time of elective catheter ablation. It may improve the safety or effectiveness of the procedure by targeting a pathway involved in heart rhythm events.

Indianapolis, Indiana

Hear when a new Intra-operative Hypotension trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.