Testing how a new enema routine changes gut bacteria
Part of Digestive system clinical trials.
This study looks at how placing an antegrade (forward-flow) continence enema and starting a bowel flush routine may change your gut microbiome (your gut bacteria). It is meant for children who have long-lasting constipation that required a special surgical drainage channel.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have long-term functional constipation that has required a MACE appendicostomy or cecostomy
- Your colon’s movement is intact, based on prior testing (CMS studies)
- Your constipation is not caused by a structural problem or another medical/anatomic disease
- You have not had prior gastrointestinal surgery (except placing G or GJ tubes)
- You have not had severe other gut illnesses unrelated to your constipation
- You have not taken probiotics, prebiotics, or antibiotics in the last month
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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