Clin2
NCT05835804Worth exploringNot yet recruiting

Chemotherapy and Immunotherapy for Head and Neck Cancer That Has Returned

Squamous Cell Carcinoma of the Head and NeckPaclitaxelCarboplatinNivolumab

Part of Cancer clinical trials.

This trial is testing whether giving a combination of chemotherapy drugs directly into the tumor along with an immunotherapy drug called nivolumab given through an IV can help when head or neck cancer has come back in the same area. The goal is to control the local tumor when other standard treatments haven't worked.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
39 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be 18 or older and able to do normal activities (fully active, up and about, or limited in strenuous work but not in light work).
  • Your head or neck cancer must have come back in the same area after standard treatments like surgery, radiation, chemotherapy, or the drug cetuximab.
  • You must have already tried the immunotherapy drug nivolumab and it wasn't effective enough.
  • Your doctor needs to be able to see the tumor on a scan or exam (and if it has spread, that must not be life-threatening).
  • Your blood counts and liver and kidney function must be within safe limits (your doctor will check these).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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