Testing weekly vs every 3 weeks ondansetron for chemo nausea
Treatments studied
Part of Cancer, Digestive system clinical trials.
This trial compares two schedules of ondansetron (a nausea prevention drug) in people getting cisplatin chemotherapy plus a PD-1 inhibitor. It aims to find which dosing schedule works best to prevent nausea and vomiting.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 or older.
- You must have a solid tumor cancer confirmed by biopsy.
- You must be about to start treatment with cisplatin chemotherapy along with a PD-1 inhibitor.
- Your tumor's PD-L1 level (TPS) must be greater than 1%.
- Your blood counts and kidney/liver function must be within certain safe levels.
- You must be well enough to carry out daily activities (ECOG 0 or 1).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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