Clin2
NCT06140992Possibly a fitRecruiting

A trial to classify cancer of unknown primary

Unknown Primary TumorsDNA Methylation

Part of Cancer clinical trials.

This trial is for people whose cancer started in an unknown place (cancer of unknown primary). It uses a special test called PaCIFiC-CUP to help classify the cancer, which may guide better treatment choices.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
120 people
Ages
18 years to 80 years
Study type
Observational

Who can take part

  • You have a tumor sample that you gave permission to use for research.
  • Your cancer was diagnosed as a primary site unknown tumor (the doctors don't know where it started).
  • You have already received some kind of treatment for your cancer (like chemotherapy).
  • Your doctors have your complete medical and lab records.
  • You are able to get up and take care of yourself (ECOG score 0-2).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06695494Recruiting
Genomic testing for cancer of unknown primary

This trial is for people with cancer of unknown primary (CUP), meaning cancer that started in an unknown place in the body. It aims to use advanced genomic testing (looking at your tumor's DNA) on your stored tumor sample and blood to find clues about where the cancer began and possible treatment options.

Manchester, Greater Manchester
NCT07366008Not yet recruiting
Improving care for cancer of unknown primary

This study is for people with cancer that has spread to other parts of the body but where doctors cannot find the original tumor (called cancer of unknown primary). The trial aims to improve prediction of how the cancer will behave and to personalize treatment. Participants will have a biopsy of the metastatic area, and researchers will use this to better understand the cancer and guide treatment options.

Bergen
NCT07761429Recruiting· Phase 2/Phase 3
Study of a new drug with chemo for cancer of unknown primary

This trial tests a new drug (F520) combined with two chemotherapy drugs for people whose cancer started in an unknown place in the body. It aims to see if the combination shrinks tumors and is safe.

Shanghai, Shanghai Municipality
NCT07434180Not yet recruiting· Phase 2
Targeted radiation for cancer of unknown primary

This trial tests a radioactive medicine (Lu-177 FAP-2286) that seeks out and delivers radiation directly to cancer cells. It is for people whose cancer started in an unknown place and has not responded to their first chemotherapy.

Melbourne, Victoria
NCT07712965Not yet recruiting
Living with cancer of unknown primary: a patient experience study

This study aims to understand the experiences of people living with cancer of unknown primary (CUP) and their caregivers. By sharing your story, you can help improve support and care for others in the same situation.

NCT04504604Recruiting
Study matching rare cancer care with tumor DNA testing

This study looks at people with rare solid tumors or lymphoma to understand their cancer’s genetic changes. It collects blood and existing tissue samples (from standard care) for DNA testing and gathers health information to help improve knowledge about rare cancers.

Cambridge, Massachusetts

Hear when a new Unknown Primary Tumors trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.