Personalized versus standard treatment for H. pylori infection
Part of Digestive system, Infections clinical trials.
This study is testing whether giving H. pylori treatment based on the specific bacteria found in your stomach works better than the standard one-size-fits-all approach. If you are already getting an endoscopy with a biopsy, this trial could help find the most effective medication for your infection.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older and planning to have an upper endoscopy with a biopsy (a procedure that takes a small tissue sample from your stomach).
- You cannot have taken antibiotics in the past month.
- You cannot have taken a proton pump inhibitor (like omeprazole) in the past 2 weeks.
- You must not have been treated for H. pylori before.
- You cannot have had stomach surgery to remove part of your stomach, and you must be Portuguese.
- You must not be pregnant or breastfeeding, and if you are a woman of childbearing age, you must use effective birth control.
- You cannot have an allergy to amoxicillin (a common antibiotic), serious health conditions, or be on blood thinners.
- During the endoscopy, you cannot have stomach cancer, bleeding in the stomach, or enlarged veins in the stomach.
- The biopsy must show that you actually have an H. pylori infection.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a simpler two-drug treatment for H. pylori infection, chosen based on a stool test that checks if the bacteria are resistant to clarithromycin. It may help people who have not been treated before avoid unnecessary antibiotics.
This study compares two ways to treat Helicobacter pylori (H. pylori) infection that didn’t go away with prior therapy. One approach uses test results to guide which medicines to use, and the other uses standard (“empiric”) treatment. The goal is to see which works better and more safely as a rescue plan.
This study tests a new way to choose antibiotics for H. pylori infection when the usual treatment has failed. By looking at your stool sample, doctors can pick the medicine most likely to work for you.
This study tests whether adding a probiotic (a healthy bacteria supplement) to the standard four-drug treatment for H. pylori infection helps get rid of the bacteria better and with fewer side effects. It may help make your treatment more effective and easier to tolerate.
This trial checks teenagers for a long-lasting H. pylori stomach infection and then treats those who need it. It may help prevent ongoing stomach problems from the infection and compare outcomes between treated and non-treated groups.
This study compares a treatment plan that is customized to the person's genes with the usual standard care for getting rid of H. pylori, a common stomach infection. The goal is to see if the personalized approach works better for veterans.
Hear when a new Helicobacter Pylori Infection trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.