Alpha radiation therapy for breast cancer in older or frail patients
Part of Cancer, Skin clinical trials.
This trial tests a new type of radiation therapy (DaRT) that uses tiny, implantable seeds to deliver targeted alpha radiation to breast tumors. It is designed for older patients (65+) or those who are too frail for surgery, offering a less invasive option for controlling the cancer.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have invasive breast cancer that has not spread to the skin within the last year.
- The tumor must be 4 cm or smaller (about the size of a walnut) and in a spot that can be fully covered by special radioactive seeds.
- You are 65 or older, or are younger but unable to have surgery (for example, due to health issues or personal choice).
- The cancer is either new or has come back in the same breast, but not spread to other parts of the body.
- Your overall health is fair (ECOG score 0-3, meaning you can be up and about to some extent) and you have a life expectancy of at least one year.
- Your blood counts and organ function meet basic safety levels (kidney, liver, and blood cell counts are within a certain range).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a precise type of radiation called SBRT for breast cancer in patients aged 70 or older who cannot have surgery or choose not to. The goal is to see if this treatment can effectively control the tumor without surgery.
This trial tests a treatment that places tiny radiation “seeds” inside/near the chest tumor to treat recurrent lung cancer. It may help people whose cancer has come back and can be safely reached by the radiation device.
This trial tests a targeted radiation device (DaRT seeds) to treat certain cancers on the skin, in the mouth, or in superficial soft tissue. It may help when standard treatment (like surgery or regular radiation/chemo) hasn’t worked, isn’t safe, or isn’t wanted.
This trial tests a new type of radiation using tiny alpha-emitting seeds placed directly into the tumor. It is for people whose prostate cancer came back in the gland after initial treatment but hasn't spread elsewhere.
This trial studies a radiation-emitting device (DaRT) to treat certain cancers on the skin, in the mouth, or in superficial soft tissues. You may qualify if you have a confirmed malignant tumor, enough body strength for treatment, and blood tests and pregnancy status that meet safety limits.
This trial tests a radiation treatment that places tiny radioactive seeds directly into the tumor to treat advanced pancreatic cancer. It mainly focuses on safety and whether the treatment can be delivered effectively, especially for people who may not be able to have more chemotherapy or surgery.
Hear when a new Breast cancer trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.