Clin2
NCT06243315Possibly a fitEnrolling by invitation

Long-term safety study of Ellansé-S filler for smile lines

Moderate-to-severe Nasolabial Folds (3-4 Level of WSRS Scores) on Both Sides of the Face

Part of Skin clinical trials.

This study tests the long-term safety of a dermal filler called Ellansé-S, which is made of small PCL microspheres. It is for people who want to treat moderate to deep lines from the nose to the corners of the mouth.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
374 people
Ages
18 years and older
Study type
Observational

Who can take part

  • You are 18 years or older
  • You have moderate to deep lines from your nose to the corners of your mouth (both sides)
  • You are planning to get a dermal filler made of PCL (a dissolvable material) for these lines
  • You agree to join the study, follow up with the doctors, and sign a consent form
  • You have not had any filler injections in that area within the last 1 to 2 years (depending on the type)
  • You are not pregnant, nursing, or allergic to any ingredients in the filler

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06961448Not yet recruiting
Nonsurgical filler for smile lines

This study tests a new type of filler (called polycaprolactone microspheres) to improve the appearance of nasolabial folds, commonly known as smile lines. It aims to see if this filler is safe and effective for people with moderate to severe folds.

NCT07855224Not yet recruiting
Dermal filler for smile lines improvement

This trial tests a new injectable filler to improve the appearance of smile lines (nasolabial folds) in adults. The filler is designed to smooth these lines for a more youthful look.

Cannes
NCT07255261Recruiting
Study of facial fillers for wrinkles and volume loss

This study tests several hyaluronic acid fillers to improve the look of hollows under the eyes, lips, lines around the mouth, smile lines, and cheeks. It is designed to see how well these fillers work in everyday use.

Arras
NCT07856797Not yet recruiting
Filler for smile lines around the mouth

This study tests a new filler called RADIESSE to see if it safely improves moderate to severe smile lines (nasolabial folds). If you qualify, you will receive the treatment and be monitored for results.

NCT06885775Not yet recruiting· Phase 2
Dermal filler for smile line wrinkles

This trial tests a new dermal filler to smooth moderate to severe smile lines (nasolabial folds). It aims to show the filler is safe and works well for improving these wrinkles.

Romania, Timisoara
NCT07763990Recruiting
Injectable hyaluronic acid for facial volume and lines

This study tests a new injectable filler made of hyaluronic acid (a natural substance that adds volume) to improve the look of lips, smile lines, or cheeks. If you qualify, you'll receive the treatment and be monitored for safety and results.

Tel Aviv

Hear when a new Moderate-to-severe Nasolabial Folds (3-4 Level of WSRS Scores) on Both Sides of the Face trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.