Testing ondansetron to prevent itching after C-section
Treatments studied
Part of Skin, Women’s health & pregnancy clinical trials.
This trial tests if giving ondansetron before spinal anesthesia can prevent itching that often happens after a C-section. It may help you feel more comfortable during recovery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 50 years old and having a planned C-section under spinal anesthesia.
- You have no allergies to ondansetron (Zofran), local anesthetics, or opioids.
- You are not taking certain medicines like SSRIs, antidepressants, or tramadol that could cause side effects with ondansetron.
- You do not have a prolonged heart rhythm (QTc interval) or a history of seizures or severe pre-eclampsia.
- You are willing and able to give written consent to join the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study compares two low doses of morphine given during spinal anesthesia for planned cesarean sections, to see which causes less itching. It aims to find a safer way to manage pain after birth.
This trial tests whether a medicine called ondansetron (commonly used for nausea) can help prevent low blood pressure during spinal anesthesia for planned C-sections. If you are a healthy pregnant woman with a single baby at full term and scheduled for a C-section, you may be able to join.
This study tests two common anti-nausea drugs for women having emergency C-sections under spinal anesthesia who haven't fasted. It aims to find the best way to prevent vomiting and nausea during surgery.
This trial tests if a fast-dissolving ondansetron strip placed in the mouth can help prevent shivering in patients who have had spinal anesthesia for lower body surgeries. If you are having a planned surgery on your legs, hips, or lower belly with spinal anesthesia, this might be an option for you.
This trial tests if giving anti-nausea medicine before spinal anesthesia can reduce nausea and vomiting during and after cesarean section. It may help women who receive morphine and other painkillers through the spinal injection.
This trial tests if adding ondansetron to standard spinal anesthesia during hernia surgery can provide better pain relief. It may help you need less pain medicine after the procedure.
Hear when a new Pruritus Caused by Drug trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.