Study of crofelemer for short bowel syndrome
Part of Digestive system clinical trials.
This study tests an oral drug called crofelemer in people with short bowel syndrome who need IV fluids or nutrition at least three times a week. The goal is to see if it helps reduce the need for IV support.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have short bowel syndrome and no colon in continuity.
- You need IV fluids or nutrition at least 3 times a week for the past 6 months.
- Your last bowel surgery was at least 6 months ago.
- You can eat solid or semi-solid foods and drink fluids.
- You are not currently using certain medications like teduglutide or growth hormones.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests if crofelemer can reduce diarrhea and fluid loss in people with short bowel syndrome who have a stoma (no colon connection) and need intravenous nutrition or fluids. The goal is to see if it improves gut function and quality of life.
This study tests a new treatment called FT1 for people with short bowel syndrome. It aims to help you absorb more nutrients and fluids from food, potentially reducing the need for IV nutrition.
This trial studies whether the Eclipse XL1 system is safe and may help people with short bowel syndrome, in both children and adults. It will check how well the approach works and watch for side effects over the study period.
This Phase 2 study tests whether sonefpeglutide is safe and how the body handles it (pharmacokinetics) in people with short bowel syndrome. It may help people who still need nutrition through a tube because their intestinal condition is stable.
This trial tests a new medication called glepaglutide to see if it can help people with short bowel syndrome (SBS) who need IV nutrition or fluids at least 3 days a week. The goal is to reduce or even stop the need for these IV treatments.
This trial tests a new medicine called PJ009 for people with short bowel syndrome who need intravenous (IV) nutrition support. It aims to help reduce the need for IV nutrition. To join, you must have been dependent on IV nutrition for at least six months and be on a stable schedule.
Hear when a new Short Bowel Syndrome trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.