Testing a diarrhea drug for short bowel syndrome without a colon
Part of Digestive system, Hormones & metabolism clinical trials.
This trial tests if crofelemer can reduce diarrhea and fluid loss in people with short bowel syndrome who have a stoma (no colon connection) and need intravenous nutrition or fluids. The goal is to see if it improves gut function and quality of life.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 or older.
- You have short bowel syndrome with a stoma (jejunostomy, ileostomy, or duodenostomy) and need IV fluids or nutrition at least 3 days a week.
- You have had loose, watery stools for more than 4 weeks.
- At least 6 months have passed since your last bowel surgery, and you are not planning more surgery during the study.
- You have at least 60 cm of small intestine left.
- If you have Crohn's disease, it must be inactive (in remission) for at least 12 weeks.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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